Literature DB >> 8503537

Pathophysiology of spinal cord trauma.

D K Anderson1, E D Hall.   

Abstract

This article reviews the pathophysiology of spinal cord injury. The focus is on the role of post-traumatic membrane lipid changes, including lipid hydrolysis with enzymatic lipid peroxidation (ie, eicosanoid production) and nonenzymatic, free radical-induced lipid peroxidation in the secondary autodestruction of injured spinal cord tissue. A speculative etiopathogenesis of secondary injury is presented in an attempt to explain the importance and order of the pathophysiologic events that result in tissue death and the apparent effectiveness of diverse pharmacologic agents in the treatment of experimental spinal cord injury.

Entities:  

Mesh：

Year:  1993        PMID： 8503537     DOI： 10.1016/s0196-0644(05)82739-8

Source DB:  PubMed          Journal:  Ann Emerg Med        ISSN： 0196-0644            Impact factor:   5.721


  55 in total

1.  A reassessment of P2X7 receptor inhibition as a neuroprotective strategy in rat models of contusion injury.

Authors:  Alexander Marcillo; Beata Frydel; Helen M Bramlett; W Dalton Dietrich
Journal:  Exp Neurol       Date:  2011-11-10       Impact factor: 5.330

2.  Loss and spontaneous recovery of forelimb evoked potentials in both the adult rat cuneate nucleus and somatosensory cortex following contusive cervical spinal cord injury.

Authors:  Stephen M Onifer; Christine D Nunn; Julie A Decker; Beth N Payne; Michelle R Wagoner; Aaron H Puckett; James M Massey; James Armstrong; Ezidin G Kaddumi; Kimberly G Fentress; Michael J Wells; Robert M West; Charles C Calloway; Jeffrey T Schnell; Christopher M Whitaker; Darlene A Burke; Charles H Hubscher
Journal:  Exp Neurol       Date:  2007-06-30       Impact factor: 5.330

3.  Evaluation of the neuroprotective effects of citicoline after experimental spinal cord injury: improved behavioral and neuroanatomical recovery.

Authors:  Neslihan Yücel; Süleyman R Cayli; Ozkan Ateş; Neşe Karadağ; Serpil Firat; Yusuf Turköz
Journal:  Neurochem Res       Date:  2006-06-21       Impact factor: 3.996

Review 4.  Neuroprotection and acute spinal cord injury: a reappraisal.

Authors:  Edward D Hall; Joe E Springer
Journal:  NeuroRx       Date:  2004-01

Review 5.  Cellular transplantation strategies for spinal cord injury and translational neurobiology.

Authors:  Paul J Reier
Journal:  NeuroRx       Date:  2004-10

6.  New concept of pathogenesis of impaired circulation in traumatic cervical spinal cord injury and its impact on disease severity: case series of four patients.

Authors:  M Salkov; V Tsymbaliuk; L Dzyak; A Rodinsky; Y Cherednichenko; G Titov
Journal:  Eur Spine J       Date:  2015-05-15       Impact factor: 3.134

7.  Genetic ablation of receptor for advanced glycation end products promotes functional recovery in mouse model of spinal cord injury.

Authors:  Ji-Dong Guo; Li Li; Ya-Min Shi; Hua-Dong Wang; Yan-Li Yuan; Xiu-Xiu Shi; Shu-Xun Hou
Journal:  Mol Cell Biochem       Date:  2014-02-14       Impact factor: 3.396

8.  Rolipram attenuates acute oligodendrocyte death in the adult rat ventrolateral funiculus following contusive cervical spinal cord injury.

Authors:  Christopher M Whitaker; Eric Beaumont; Michael J Wells; David S K Magnuson; Michal Hetman; Stephen M Onifer
Journal:  Neurosci Lett       Date:  2008-04-08       Impact factor: 3.046

9.  N-acetylcysteine amide preserves mitochondrial bioenergetics and improves functional recovery following spinal trauma.

Authors:  Samir P Patel; Patrick G Sullivan; Jignesh D Pandya; Glenn A Goldstein; Jenna L VanRooyen; Heather M Yonutas; Khalid C Eldahan; Johnny Morehouse; David S K Magnuson; Alexander G Rabchevsky
Journal:  Exp Neurol       Date:  2014-05-05       Impact factor: 5.330

10.  The effect of duration of compression on lipid peroxidation after experimental spinal cord injury.

Authors:  M Y Kaynar; M Hanci; A Kafadar; K Gümüştaş; A Belce; N Ciplak
Journal:  Neurosurg Rev       Date:  1998       Impact factor: 3.042
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.