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Literature DB >> 8503146

Citrate and urease-induced crystallization in synthetic and human urine.

Y H Wang¹, L Grenabo, H Hedelin, R J McLean, J C Nickel, S Pettersson.

Abstract

The effects of citrate on the different phases of urease-induced crystallization were studied using Coulter counter techniques and optical microscopy. Citrate increased urine pH and markedly delayed the initiation of the crystallization (nucleation) in both human and synthetic urine. In synthetic urine, particle aggregation and especially particle growth were delayed and inhibited by citrate. In human urine, aggregation was distinctly inhibited by citrate. It appears that the susceptibility of urine to form crystals in the presence of urease activity is influenced by its citrate concentration.

Entities: Chemical Disease Species

Mesh：

Substances：
Citrates
Urease

Year: 1993 PMID： 8503146 DOI： 10.1007/BF01788828

Source DB: PubMed Journal: Urol Res ISSN： 0300-5623

19 in total

1. Effects of serum, albumin and immunoglobulins on urease-induced crystallization in urine.

Authors: J Hugosson; L Grenabo; H Hedelin; S Pettersson
Journal: Urol Res Date: 1990

2. Studies of urease-induced crystallisation in undiluted human urine using the Coulter counter technique.

Authors: Y H Wang; L Grenabo; H Hedelin; S Holmäng; S Pettersson
Journal: Urol Res Date: 1991

3. The effects of fractioned human urine on urease-induced crystallisation in vitro.

Authors: H Hedelin; L Grenabo; S Petterson
Journal: Urol Res Date: 1990

4. Bacteriology of upper urinary tract stones.

Authors: J Hugosson; L Grenabo; H Hedelin; S Pettersson; S Seeberg
Journal: J Urol Date: 1990-05 Impact factor: 7.450

5. The inhibitory effect of human urine on urease-induced crystallization in vitro.

Authors: L Grenabo; H Hedelin; S Pettersson
Journal: J Urol Date: 1986-02 Impact factor: 7.450

6. Variations in the activity of urinary inhibitors in calcium oxalate urolithiasis.

Authors: F Grases; C Genestar; P March; A Conte
Journal: Br J Urol Date: 1988-12

7. Enzymic determination of citrate in serum and urine, with use of the Worthington "ultrafree" device.

Authors: D Tompkins; J Toffaletti
Journal: Clin Chem Date: 1982-01 Impact factor: 8.327

8. Influence of chondroitin sulfate, heparin sulfate, and citrate on Proteus mirabilis-induced struvite crystallization in vitro.

Authors: R J McLean; J Downey; L Clapham; J C Nickel
Journal: J Urol Date: 1990-11 Impact factor: 7.450

Citrate and urease-induced crystallization in synthetic and human urine.

1. Effects of serum, albumin and immunoglobulins on urease-induced crystallization in urine.

2. Studies of urease-induced crystallisation in undiluted human urine using the Coulter counter technique.

3. The effects of fractioned human urine on urease-induced crystallisation in vitro.

4. Bacteriology of upper urinary tract stones.

5. The inhibitory effect of human urine on urease-induced crystallization in vitro.

6. Variations in the activity of urinary inhibitors in calcium oxalate urolithiasis.

7. Enzymic determination of citrate in serum and urine, with use of the Worthington "ultrafree" device.

8. Influence of chondroitin sulfate, heparin sulfate, and citrate on Proteus mirabilis-induced struvite crystallization in vitro.

9. Inhibitory effect of pyrophosphate, citrate, magnesium and chondroitin sulphate in calcium oxalate urolithiasis.

10. Urease-induced crystallization in synthetic urine.

Review 1. Encrustation of biomaterials in the urinary tract.

2. Modelling crystal aggregation and deposition in the catheterised lower urinary tract.

3. Is citrate an inhibitor of calcium oxalate crystal growth in high concentrations of urine?

4. Unique ability of the Proteus mirabilis capsule to enhance mineral growth in infectious urinary calculi.

5. Biomimetic synthesis of struvite with biogenic morphology and implication for pathological biomineralization.