Persistence of multiple serovars of Neisseria gonorrhoeae.

Two simple mathematical models of gonococcal transmission dynamics that allow for heterogeneity within the pathogen were assessed. Models were compared for their ability to mirror the observed persistence of different gonococcal serovars over time and differential distribution within subgroups of the total population. Serotyping data collected between the periods of 1984-1988 and 1988-1990 were analyzed for differences in serovar distribution. The data show persistence of multiple serovars within both homosexual and heterosexual contact groups over time. The models provide a framework for the use of phenotypic markers to assess behavior change in sexually active populations.