Literature DB >> 8501573

Abnormalities of the corrected QT interval in familial dysautonomia: an indicator of autonomic dysfunction.

J S Glickstein1, D Schwartzman, D Friedman, M Rutkowski, F B Axelrod.   

Abstract

We report abnormalities in corrected QT intervals with changes in position and after exercise in patients with familial dysautonomia and confirm the previously reported finding of abnormal heart rate and blood pressure responses. Prolonged corrected QT intervals (> 440 msec) with lack of appropriate shortening with exercise is a noninvasive means of demonstrating an aberration in autonomic regulation of cardiac conduction.

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Year:  1993        PMID: 8501573     DOI: 10.1016/s0022-3476(09)90022-1

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  15 in total

1.  Quantitative sensory testing of thermal and vibratory perception in familial dysautonomia.

Authors:  M J Hilz; F B Axelrod
Journal:  Clin Auton Res       Date:  2000-08       Impact factor: 4.435

2.  Electrocardiographic repolarization abnormalities in familial dysautonomia: an indicator of cardiac autonomic dysfunction.

Authors:  J S Glickstein; F B Axelrod; D Friedman
Journal:  Clin Auton Res       Date:  1999-04       Impact factor: 4.435

3.  Pattern of plasma levels of catecholamines in familial dysautonomia.

Authors:  F B Axelrod; D S Goldstein; C Holmes; D Berlin; I J Kopin
Journal:  Clin Auton Res       Date:  1996-08       Impact factor: 4.435

Review 4.  Familial dysautonomia (Riley-Day syndrome).

Authors:  A Shetty; P Parikh; R P Khubchandani
Journal:  Indian J Pediatr       Date:  1995 May-Jun       Impact factor: 1.967

5.  Sympathetic skin response following thermal, electrical, acoustic, and inspiratory gasp stimulation in familial dysautonomia patients and healthy persons.

Authors:  M J Hilz; F B Azelrod; G Schweibold; E H Kolodny
Journal:  Clin Auton Res       Date:  1999-08       Impact factor: 4.435

Review 6.  Pacemakers in patients with familial dysautonomia--a review of experience with 20 patients.

Authors:  Gabrielle Gold-von Simson; Monika Rutkowski; Dena Berlin; Felicia B Axelrod
Journal:  Clin Auton Res       Date:  2005-02       Impact factor: 4.435

7.  Highly abnormal thermotests in familial dysautonomia suggest increased cardiac autonomic risk.

Authors:  M J Hilz; E H Kolodny; I Neuner; B Stemper; F B Axelrod
Journal:  J Neurol Neurosurg Psychiatry       Date:  1998-09       Impact factor: 10.154

8.  Association between C-reactive protein and QTc interval in middle-aged men and women.

Authors:  Eunhee Kim; SoonJae Joo; Jinyoung Kim; JeongCheon Ahn; JeHyeong Kim; Kuchan Kimm; Chol Shin
Journal:  Eur J Epidemiol       Date:  2006-10-27       Impact factor: 8.082

Review 9.  The molecular basis of familial dysautonomia: overview, new discoveries and implications for directed therapies.

Authors:  Berish Y Rubin; Sylvia L Anderson
Journal:  Neuromolecular Med       Date:  2007-11-06       Impact factor: 3.843

10.  Documented transient third-degree atrioventricular block and asystole in a child with familial dysautonomia.

Authors:  Amichay Rotstein; Joel Charrow; Barbara J Deal
Journal:  Pediatr Cardiol       Date:  2007-09-13       Impact factor: 1.655

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