| Literature DB >> 850086 |
T D Wilkins, C B Walker, D Nitzan, A A Salyers.
Abstract
Experimental anaerobic infections in mice are reviewed with a description of a model of pure Bacteroides fragilis infection. In this experimental situation, B. fragilis produces large subcutaneous abscesses in the groins of mice that can be diagnosed without autopsy. This infection was treated effectively with clindamycin in doses that produced levels of drug in blood similar to those attainable in humans.Entities:
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Year: 1977 PMID： 850086 DOI： 10.1093/infdis/135.supplement.s13
Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226