| Literature DB >> 8499426 |
B L Adams1, L B Warneke, A J McEwan, B A Fraser.
Abstract
Patterns of cerebral perfusion in patients with obsessive compulsive disorder were evaluated using single photon emission computerized tomography. Eleven patients, who satisfied the DSM-III-R criteria and Research Diagnostic Criteria for the disorder, were evaluated using the distribution of 99m-Tc-HMPAO as a radiotracer. The Yale-Brown Obsessive Compulsive Scale was administered to each patient to assess the severity of their symptoms. The images obtained were evaluated qualitatively and semi-quantitatively by a physician in nuclear medicine who was blind to the patients' diagnoses. Eight of the 11 patients demonstrated asymmetric perfusion of the basal ganglia; the left side showed impaired perfusion in six patients.Entities:
Mesh:
Year: 1993 PMID: 8499426 PMCID: PMC1188506
Source DB: PubMed Journal: J Psychiatry Neurosci ISSN: 1180-4882 Impact factor: 6.186