| Literature DB >> 8498562 |
H Uchizumi1, R Hattori, K Sase, W J Cai, K Kadota, S Sasayama, C Kawai, Y Yui.
Abstract
It has been known that cytotoxic-activated macrophages release an unstable vasorelaxing substance, nitric oxide. We have found that a more stable relaxing factor is released from those cells. This factor seems to be synthesized from L-arginine. It acts through the activation of soluble guanylate cyclase without affecting membrane potential. It has little charge at nearly neutral pH, and its molecular weight is < 500.Entities:
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Year: 1993 PMID： 8498562 DOI： 10.1152/ajpheart.1993.264.5.H1472
Source DB: PubMed Journal: Am J Physiol ISSN： 0002-9513