Literature DB >> 8497067

Legitimate and illegitimate cleavage of human immunodeficiency virus glycoproteins by furin.

Y Morikawa1, E Barsov, I Jones.   

Abstract

Coexpression of human immunodeficiency virus type 1 glycoproteins with the subtilisin-like protease furin leads to processing of gp160 and gp140, a truncated form of gp160, to gp120. In addition, we show that gp120 itself is further cleaved by furin at sites near the primary cleavage site and within the V3 loop.

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Year:  1993        PMID: 8497067      PMCID: PMC237708          DOI: 10.1128/JVI.67.6.3601-3604.1993

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  28 in total

Review 1.  Mammalian subtilisins: the long-sought dibasic processing endoproteases.

Authors:  P J Barr
Journal:  Cell       Date:  1991-07-12       Impact factor: 41.582

2.  The protease and gag gene products of the human immunodeficiency virus: authentic cleavage and post-translational modification in an insect cell expression system.

Authors:  H A Overton; Y Fujii; I R Price; I M Jones
Journal:  Virology       Date:  1989-05       Impact factor: 3.616

3.  Complementation of human immunodeficiency virus glycoprotein mutations in trans.

Authors:  Y Morikawa; J P Moore; E Fenouillet; I M Jones
Journal:  J Gen Virol       Date:  1992-08       Impact factor: 3.891

4.  Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes.

Authors:  R L Willey; F Maldarelli; M A Martin; K Strebel
Journal:  J Virol       Date:  1992-01       Impact factor: 5.103

5.  "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A.

Authors:  W N Burnette
Journal:  Anal Biochem       Date:  1981-04       Impact factor: 3.365

6.  Small amino acid changes in the V3 hypervariable region of gp120 can affect the T-cell-line and macrophage tropism of human immunodeficiency virus type 1.

Authors:  T Shioda; J A Levy; C Cheng-Mayer
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

7.  Mammalian subtilisin-related proteinases in cleavage activation of the paramyxovirus fusion glycoprotein: superiority of furin/PACE to PC2 or PC1/PC3.

Authors:  B Gotoh; Y Ohnishi; N M Inocencio; E Esaki; K Nakayama; P J Barr; G Thomas; Y Nagai
Journal:  J Virol       Date:  1992-11       Impact factor: 5.103

8.  Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus.

Authors:  J M McCune; L B Rabin; M B Feinberg; M Lieberman; J C Kosek; G R Reyes; I L Weissman
Journal:  Cell       Date:  1988-04-08       Impact factor: 41.582

9.  Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160.

Authors:  S Hallenberger; V Bosch; H Angliker; E Shaw; H D Klenk; W Garten
Journal:  Nature       Date:  1992-11-26       Impact factor: 49.962

10.  Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.

Authors:  A Stieneke-Gröber; M Vey; H Angliker; E Shaw; G Thomas; C Roberts; H D Klenk; W Garten
Journal:  EMBO J       Date:  1992-07       Impact factor: 11.598

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  28 in total

1.  Variable-loop-deleted variants of the human immunodeficiency virus type 1 envelope glycoprotein can be stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits.

Authors:  R W Sanders; L Schiffner; A Master; F Kajumo; Y Guo; T Dragic; J P Moore; J M Binley
Journal:  J Virol       Date:  2000-06       Impact factor: 5.103

2.  Identification of two sequences in the cytoplasmic tail of the human immunodeficiency virus type 1 envelope glycoprotein that inhibit cell surface expression.

Authors:  A Bültmann; W Muranyi; B Seed; J Haas
Journal:  J Virol       Date:  2001-06       Impact factor: 5.103

3.  A chimeric protein of simian immunodeficiency virus envelope glycoprotein gp140 and Escherichia coli aspartate transcarbamoylase.

Authors:  Bing Chen; Yifan Cheng; Lesley Calder; Stephen C Harrison; Ellis L Reinherz; John J Skehel; Don C Wiley
Journal:  J Virol       Date:  2004-05       Impact factor: 5.103

4.  Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization.

Authors:  James M Binley; Yih-En Andrew Ban; Emma T Crooks; Dirk Eggink; Keiko Osawa; William R Schief; Rogier W Sanders
Journal:  J Virol       Date:  2010-03-24       Impact factor: 5.103

5.  Human Ubc9 contributes to production of fully infectious human immunodeficiency virus type 1 virions.

Authors:  Tareq Jaber; Christopher R Bohl; Gentry L Lewis; Charles Wood; John T West; Robert A Weldon
Journal:  J Virol       Date:  2009-07-29       Impact factor: 5.103

6.  A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure.

Authors:  J M Binley; R W Sanders; B Clas; N Schuelke; A Master; Y Guo; F Kajumo; D J Anselma; P J Maddon; W C Olson; J P Moore
Journal:  J Virol       Date:  2000-01       Impact factor: 5.103

7.  Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered alpha 2-macroglobulin containing a furin recognition sequence in the bait region.

Authors:  L Van Rompaey; T Ayoubi; W Van De Ven; P Marynen
Journal:  Biochem J       Date:  1997-09-01       Impact factor: 3.857

8.  A furin-defective cell line is able to process correctly the gp160 of human immunodeficiency virus type 1.

Authors:  Y Ohnishi; T Shioda; K Nakayama; S Iwata; B Gotoh; M Hamaguchi; Y Nagai
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

Review 9.  The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.

Authors:  S Bour; R Geleziunas; M A Wainberg
Journal:  Microbiol Rev       Date:  1995-03

10.  Engineered serine protease inhibitor prevents furin-catalyzed activation of the fusion glycoprotein and production of infectious measles virus.

Authors:  M Watanabe; A Hirano; S Stenglein; J Nelson; G Thomas; T C Wong
Journal:  J Virol       Date:  1995-05       Impact factor: 5.103

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