Literature DB >> 8492636

Demonstration of the myocardial salvage effect of lithospermic acid B isolated from the aqueous extract of Salvia miltiorrhiza.

K P Fung1, L H Zeng, J Wu, H N Wong, C M Lee, P M Hon, H M Chang, T W Wu.   

Abstract

Lithospermic acid B has been isolated to > 95% purity by high performance liquid chromatography from the aqueous extract of the roots of Salvia miltiorrhiza. When infused at 5.5 mumoles/kg into the post-ischemic rabbit heart, it reduced by 62 +/- 10% (n = 8) the myocardial damage found in the saline control in a rabbit ischemia-reperfusion model.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8492636     DOI： 10.1016/0024-3205(93)90471-e

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  9 in total

1.  Pharmacokinetics of depside salts from Salvia miltiorrhiza in healthy Chinese volunteers: A randomized, open-label, single-dose study.

Authors:  Jing-Ying Jia; You-Li Lu; Xiao-Chuan Li; Gang-Yi Liu; Shui-Jun Li; Yun Liu; Yan-Mei Liu; Chen Yu; Yi-Ping Wang
Journal:  Curr Ther Res Clin Exp       Date:  2010-08

2.  Salvia miltiorrhiza water-soluble extract, but not its constituent salvianolic acid B, abrogates LPS-induced NF-kappaB signalling in intestinal epithelial cells.

Authors:  J S Kim; A S Narula; C Jobin
Journal:  Clin Exp Immunol       Date:  2005-08       Impact factor: 4.330

Review 3.  Biological screening of natural products and drug innovation in China.

Authors:  Ming-Wei Wang; Xiaojiang Hao; Kaixian Chen
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2007-06-29       Impact factor: 6.237

4.  Salvianolate inhibits cytokine gene expression in small intestine of cirrhotic rats.

Authors:  Dan-Hong Yang; Zai-Yuan Ye; Bo Jin; Xu-Jun He; Qin Zhang; Wei-Ming Zhou; Wen-Juan Xu; Huo-Xiang Lu
Journal:  World J Gastroenterol       Date:  2011-04-14       Impact factor: 5.742

5.  Effect of salvianolate on intestinal epithelium tight junction protein zonula occludens protein 1 in cirrhotic rats.

Authors:  Dan-Hong Yang; Zai-Yuan Ye; Yuan-Jun Xie; Xu-Jun He; Wen-Juan Xu; Wei-Ming Zhou
Journal:  World J Gastroenterol       Date:  2012-12-21       Impact factor: 5.742

Review 6.  Salvia miltiorrhizaBurge (Danshen): a golden herbal medicine in cardiovascular therapeutics.

Authors:  Zhuo-Ming Li; Suo-Wen Xu; Pei-Qing Liu
Journal:  Acta Pharmacol Sin       Date:  2018-04-26       Impact factor: 6.150

7.  2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran promotes endothelial nitric oxide synthase activity in human endothelial cells.

Authors:  Angela Ladurner; Atanas G Atanasov; Elke H Heiss; Lisa Baumgartner; Stefan Schwaiger; Judith M Rollinger; Hermann Stuppner; Verena M Dirsch
Journal:  Biochem Pharmacol       Date:  2012-07-06       Impact factor: 5.858

8.  Novel anti-infective potential of salvianolic acid B against human serious pathogen Neisseria meningitidis.

Authors:  Sanna Huttunen; Marko Toivanen; Chenghai Liu; Carina Tikkanen-Kaukanen
Journal:  BMC Res Notes       Date:  2016-01-13

9.  Cardiovascular Protective Effects of Adjunctive Alternative Medicine (Salvia miltiorrhiza and Pueraria lobata) in High-Risk Hypertension.

Authors:  K S Woo; Thomas W C Yip; Ping Chook; S K Kwong; C C Szeto; June K Y Li; Alex W Y Yu; William K F Cheng; Thomas Y K Chan; K P Fung; P C Leung
Journal:  Evid Based Complement Alternat Med       Date:  2013-03-07       Impact factor: 2.629
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.