Literature DB >> 849255

Electrophoresis of human l-glutamate dehydrogenase: tissue distribution and preliminary population survey.

R L Nelson, M S Povey, D A Hopkinson, H Harris.   

Abstract

A method for the starch gel electrophoresis of human L-glutamate dehydrogenase (GLUD) is described, as is the tissue distribution of GLUD detected by this method. Extracts of livers from 200 Whites were analyzed without demonstration of an electrophoretic variant. The molecular size was estimated to be 330,000 and the isoelectric point pH 4.83.

Entities:  

Mesh:

Substances:

Year:  1977        PMID: 849255     DOI: 10.1007/BF00484550

Source DB:  PubMed          Journal:  Biochem Genet        ISSN: 0006-2928            Impact factor:   1.890


  15 in total

1.  L-Glutamate dehydrogenase isoenzymes.

Authors:  H van der HELM
Journal:  Nature       Date:  1962-05-26       Impact factor: 49.962

2.  MULTIPLE FORMS OF ENZYMES: TISSUE, ONTOGENETIC, AND SPECIES SPECIFIC PATTERNS.

Authors:  C L Markert; F Møller
Journal:  Proc Natl Acad Sci U S A       Date:  1959-05       Impact factor: 11.205

3.  Conformational changes and the regulation of glutamate-dehydrogenase activity.

Authors:  P M Bayley; G K Radda
Journal:  Biochem J       Date:  1966-01       Impact factor: 3.857

4.  On the role of amino groups in the structure and function of glutamate dehydrogenase. II. Effect of acetylation on molecular properties.

Authors:  R F Colman; C Frieden
Journal:  J Biol Chem       Date:  1966-08-25       Impact factor: 5.157

5.  Purification and properties of cytidine deaminase from normal and leukemic granulocytes.

Authors:  B A Chabner; D G Johns; C N Coleman; J C Drake; W H Evans
Journal:  J Clin Invest       Date:  1974-03       Impact factor: 14.808

6.  Evolution of enzyme regulator sites: evidence for partial gene duplication from amino-acid sequence of bovine glutamate dehydrogenase.

Authors:  P C Engel
Journal:  Nature       Date:  1973-01-12       Impact factor: 49.962

7.  Allosteric transitions of glutamate dehydrogenase.

Authors:  A D Malcolm; G K Radda
Journal:  Nature       Date:  1968-08-31       Impact factor: 49.962

8.  The coenzyme-binding domains of glutamate dehydrogenases.

Authors:  J C Wootton
Journal:  Nature       Date:  1974-12-13       Impact factor: 49.962

9.  Enzymes involved in glutamate metabolism in legume root nodules.

Authors:  H Grimes; P F Fottrell
Journal:  Nature       Date:  1966-10-15       Impact factor: 49.962

10.  Isoenzymatic nature of L-glutamic dehydrogenase of higher plants.

Authors:  D A Thurman; C Palin; M V Laycock
Journal:  Nature       Date:  1965-07-10       Impact factor: 49.962

View more
  5 in total

1.  Detection after electrophoresis of enzymes involved in ammonia metabolism using L-glutamate dehydrogenase as a linking enzyme.

Authors:  R L Nelson; S Povey; D A Hopkinson; H Harris
Journal:  Biochem Genet       Date:  1977-12       Impact factor: 1.890

Review 2.  Biomarkers of drug-induced liver injury: progress and utility in research, medicine, and regulation.

Authors:  Mitchell R McGill; Hartmut Jaeschke
Journal:  Expert Rev Mol Diagn       Date:  2018-08-13       Impact factor: 5.225

3.  Analysis of L-alanine:2-oxoglutarate aminotransferase isozymes in maize.

Authors:  N R Watson; V M Peschke; D A Russell; M M Sachs
Journal:  Biochem Genet       Date:  1992-08       Impact factor: 1.890

Review 4.  Biomarkers of drug-induced liver injury: a mechanistic perspective through acetaminophen hepatotoxicity.

Authors:  David S Umbaugh; Hartmut Jaeschke
Journal:  Expert Rev Gastroenterol Hepatol       Date:  2020-12-09       Impact factor: 3.869

Review 5.  Oxidative Stress in Drug-Induced Liver Injury (DILI): From Mechanisms to Biomarkers for Use in Clinical Practice.

Authors:  Marina Villanueva-Paz; Laura Morán; Nuria López-Alcántara; Cristiana Freixo; Raúl J Andrade; M Isabel Lucena; Francisco Javier Cubero
Journal:  Antioxidants (Basel)       Date:  2021-03-05
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.