Literature DB >> 849246

Relationship between enzyme heterozygosity and quaternary structure.

R D Ward.   

Abstract

The need for proteins to maintain particular quarternary structures constrains variability in amino acid sequence. Monomeric enzymes are then expected to be more variable than dimeric forms, which in turn are expected to be more variable than tetrameric forms. These predictions are confirmed by analysis of available data on enzyme variation. Theories relating enzyme heterozygosity to metabolic function are discussed in the light of these findings.

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Year:  1977        PMID: 849246     DOI: 10.1007/BF00484555

Source DB:  PubMed          Journal:  Biochem Genet        ISSN: 0006-2928            Impact factor:   1.890


  53 in total

1.  Genetic polymorphism and evolution in parthenogenetic animals. I. Polyploid curculionidae.

Authors:  E Suomalainen; A Saura
Journal:  Genetics       Date:  1973-07       Impact factor: 4.562

2.  SONG DIALECTS AND GENETIC DIFFERENCES IN WHITE-CROWNED SPARROWS (ZONOTRICHIA LEUCOPHRYS).

Authors:  Myron Charles Baker
Journal:  Evolution       Date:  1975-06       Impact factor: 3.694

3.  DEEP-SEA ASTEROIDS: HIGH GENETIC VARIABILITY IN A STABLE ENVIRONMENT.

Authors:  Francisco J Ayala; James W Valentine; Dennis Hedgecock; Lorraine G Barr
Journal:  Evolution       Date:  1975-06       Impact factor: 3.694

4.  GENETIC VARIATION IN THE HORSESHOE CRAB (LIMULUS POLYPHEMUS), A PHYLOGENETIC "RELIC".

Authors:  Robert K Selander; Suh Y Yang; Richard C Lewontin; Walter E Johnson
Journal:  Evolution       Date:  1970-06       Impact factor: 3.694

Review 5.  Mutational pressure as the main cause of molecular evolution and polymorphism.

Authors:  T Ota
Journal:  Nature       Date:  1974-11-29       Impact factor: 49.962

Review 6.  Enzyme polymorphism and metabolism.

Authors:  G B Johnson
Journal:  Science       Date:  1974-04-05       Impact factor: 47.728

7.  Age-dependent allozymic variation in a natural population of lizards.

Authors:  D W Tinkle; R K Selander
Journal:  Biochem Genet       Date:  1973-03       Impact factor: 1.890

8.  Genic variation in marginal populations of Drosophila subobscura.

Authors:  S Lakovaara; A Saura
Journal:  Hereditas       Date:  1971       Impact factor: 3.271

9.  Patterns of gene variation in central and marginal populations of Drosophila robusta.

Authors:  S Prakash
Journal:  Genetics       Date:  1973-10       Impact factor: 4.562

10.  Genetic differentiation within and between species of the Drosophila willistoni group.

Authors:  F J Ayala; M L Tracey
Journal:  Proc Natl Acad Sci U S A       Date:  1974-03       Impact factor: 11.205

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  13 in total

1.  Genetic polymorphism of sorbitol dehydrogenase in the brown hare and the distribution of the variation in central Europe.

Authors:  G B Hartl
Journal:  Biochem Genet       Date:  1991-02       Impact factor: 1.890

2.  Heterozygosity levels in a mammal: A determination derived from allele frequencies at loci controlling gross morphology.

Authors:  B Blumenberg
Journal:  Theor Appl Genet       Date:  1980-07       Impact factor: 5.699

3.  Biochemical correlates of genetic variation in marine lower invertebrates.

Authors:  A M Sole-Cava; J P Thorpe
Journal:  Biochem Genet       Date:  1989-06       Impact factor: 1.890

4.  Subunit molecular weight and genetic variability of proteins in natural populations.

Authors:  M Nei; P A Fuerst; R Chakraborty
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

5.  Contrasted modes of evolution in the same genome: allozymes and adaptive change in Heliconius.

Authors:  J R Turner; M S Johnson; W F Eanes
Journal:  Proc Natl Acad Sci U S A       Date:  1979-04       Impact factor: 11.205

6.  Genetic Differentiation between Geographically Distant Populations of DROSOPHILA MELANOGASTER.

Authors:  R S Singh; D A Hickey; J David
Journal:  Genetics       Date:  1982-06       Impact factor: 4.562

7.  Molecular evolution, intracellular organization, and the quinary structure of proteins.

Authors:  E H McConkey
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

8.  Genetic divergence between rodent species assessed by using two-dimensional electrophoresis.

Authors:  C F Aquadro; J C Avise
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

9.  Subunit size of enzymes and genetic heterozygosity in vertebrates.

Authors:  R D Ward
Journal:  Biochem Genet       Date:  1978-08       Impact factor: 1.890

10.  Heterozygosity in Yellowstone Park elk, Cervus canadensis.

Authors:  D G Cameron; E R Vyse
Journal:  Biochem Genet       Date:  1978-08       Impact factor: 1.890

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