Literature DB >> 8489670

Pediatric acepromazine poisoning: the importance of child-resistant packaging for veterinary drugs.

S D Berns1, J L Wright.   

Abstract

The first reported case of acepromazine ingestion in a pediatric patient is presented. It is an aliphatic phenothiazine that is structurally similar to chlorpromazine (thorazine). In our case, a 2 1/2-year-old male ingested 3 to 4 of his 80-pound Doberman's 25-mg tablets. The pills were stored in a vial without a child-resistant closure. The child displayed signs and symptoms of phenothiazine toxicity. There is no federal law which requires veterinary medicines to be dispensed in special packaging. All prescription medications should require child-resistant packaging.

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Year:  1993        PMID: 8489670     DOI: 10.1016/0735-6757(93)90137-z

Source DB:  PubMed          Journal:  Am J Emerg Med        ISSN: 0735-6757            Impact factor:   2.469


  2 in total

1.  Acute acepromazine overdose: clinical effects and toxicokinetic evaluation.

Authors:  D Adam Algren; Amber Ashworth
Journal:  J Med Toxicol       Date:  2015-03

2.  Acepromazine inhibits hERG potassium ion channels expressed in human embryonic kidney 293 cells.

Authors:  Young Shin Joo; Hong Joon Lee; Jin-Sung Choi; Ki-Wug Sung
Journal:  Korean J Physiol Pharmacol       Date:  2016-12-21       Impact factor: 2.016

  2 in total

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