| Literature DB >> 8488918 |
S D Trocmé1, G M Kephart, W M Bourne, R J Buckley, G J Gleich.
Abstract
An indirect immunofluorescence assay detected eosinophil granule major basic protein in the inflammatory debris covering deepithelialized cornea in two patients with vernal keratoconjunctivitis. A slight degree of non-specific fluorescence was present in the control autopsy corneas. High concentrations of the eosinophil granule major basic protein inhibit epithelial migration and protein synthesis, whereas low concentrations affect epithelial migration. The results suggest participation of eosinophil granule major basic protein in the ulcerative process.Entities:
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Year: 1993 PMID： 8488918 DOI： 10.1016/s0002-9394(14)71463-1
Source DB: PubMed Journal: Am J Ophthalmol ISSN： 0002-9394 Impact factor: 5.258