| Literature DB >> 8487220 |
A O Jorge1, M A Totti, O P de Almeida, C Scully.
Abstract
Xerostomia provoked in rats by surgical removal of the major salivary glands significantly increased oral carriage of Candida albicans. Five weeks after 3 oral inoculations of 10(8) CFU, C. albicans were found in the mouths in 50% of normal animals but after 8 weeks in none. In xerostomic rats, 100% had oral C. albicans after 5 weeks and after 18 weeks, 66.6% still harboured yeasts. Over the whole experimental period the amount of C. albicans was greater in the mouths of sialoadenectomized than in normal rats.Entities:
Mesh：
Year: 1993 PMID： 8487220 DOI： 10.1111/j.1600-0714.1993.tb01045.x
Source DB: PubMed Journal: J Oral Pathol Med ISSN： 0904-2512 Impact factor: 4.253