Literature DB >> 8486385

Polymorphic SSR (simple-sequence-repeat) markers for chromosome 20.

R Melis1, P Bradley, T Elsner, M Robertson, E Lawrence, S Gerken, H Albertsen, R White.   

Abstract

Chromosome 20-specific simple-sequence-repeat (SSR) markers were developed from a flow-sorted phage library (LL20NS01), subcloned in Bluescript, and screened with a tetranucleotide repeat, (AAAG)6, to identify potentially polymorphic loci. Of 100 clones sequenced, 39 were selected to construct primers. Of these 39, 22 were polymorphic. Reference to the CEPH linkage database (version 5) permitted genetic mapping of 16 of the new markers to specific regions of chromosome 20. Ten of the SSRs showed heterozygosity indices (above 70%) that would qualify them as potential index markers.

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Year:  1993        PMID： 8486385     DOI： 10.1006/geno.1993.1140

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  9 in total

1.  Molecular analysis of 24 Alagille syndrome families identifies a single submicroscopic deletion and further localizes the Alagille region within 20p12.

Authors:  E B Rand; N B Spinner; D A Piccoli; P F Whitington; R Taub
Journal:  Am J Hum Genet       Date:  1995-11       Impact factor: 11.025

2.  A strategy for constructing high-resolution genetic maps of the human genome: a genetic map of chromosome 17p, ordered with meiotic breakpoint-mapping panels.

Authors:  S C Gerken; H Albertsen; T Elsner; L Ballard; P Holik; E Lawrence; M Moore; X Zhao; R White
Journal:  Am J Hum Genet       Date:  1995-02       Impact factor: 11.025

3.  Physical and genetic mapping of human chromosome 3 loci containing microsatellite repeats.

Authors:  S Gerken; E Whisenant; T Varkony; S Todd; R Gemmill; C Jones; J Weissenbach; N Matsunami; M Moore; E Lawrence
Journal:  Chromosome Res       Date:  1994-11       Impact factor: 5.239

4.  Genetic mapping of the BRCA1 region on chromosome 17q21.

Authors:  H Albertsen; R Plaetke; L Ballard; E Fujimoto; J Connolly; E Lawrence; P Rodriguez; M Robertson; P Bradley; B Milner
Journal:  Am J Hum Genet       Date:  1994-03       Impact factor: 11.025

5.  Cytologically balanced t(2;20) in a two-generation family with alagille syndrome: cytogenetic and molecular studies.

Authors:  N B Spinner; E B Rand; P Fortina; A Genin; R Taub; A Semeraro; D A Piccoli
Journal:  Am J Hum Genet       Date:  1994-08       Impact factor: 11.025

6.  Isolated autosomal dominant type E brachydactyly: exclusion of linkage to candidate regions 2q37 and 20q13.

Authors:  M E Oude Luttikhuis; D K Williams; R C Trembath
Journal:  J Med Genet       Date:  1996-10       Impact factor: 6.318

7.  A collection of ordered tetranucleotide-repeat markers from the human genome. The Utah Marker Development Group.

Authors: 
Journal:  Am J Hum Genet       Date:  1995-09       Impact factor: 11.025

8.  A radiation hybrid map of the BRCA1 region.

Authors:  P O'Connell; H Albertsen; N Matsunami; T Taylor; J E Hundley; T L Johnson-Pais; B Reus; E Lawrence; L Ballard; R White
Journal:  Am J Hum Genet       Date:  1994-03       Impact factor: 11.025

9.  The gene responsible for pseudohypoparathyroidism type Ib is paternally imprinted and maps in four unrelated kindreds to chromosome 20q13.3.

Authors:  H Jüppner; E Schipani; M Bastepe; D E Cole; M L Lawson; M Mannstadt; G N Hendy; H Plotkin; H Koshiyama; T Koh; J D Crawford; B R Olsen; M Vikkula
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-29       Impact factor: 11.205
  9 in total

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