Literature DB >> 8484778

p53 gene is up-regulated during skeletal muscle cell differentiation.

O Halevy1.   

Abstract

Differentiation of cells in the mouse myogenic cell line C2, or a primary culture of chicken satellite cells was induced by low serum levels in the growth medium. Endogenous wild-type p53 mRNA was substantially expressed after approximately 5 h of incubation. Induction of p53 mRNA expression was also observed in cells treated with 10(-8) M retinoic acid, after 18 h of incubation. In both cases, the increase in p53 mRNA was transient. c-fos mRNA levels decreased rapidly and were barely detectable after 2 h of exposure to retinoic acid. The down-regulation of c-fos confirms its role in muscle cell differentiation, whereas the up-regulation of wild-type p53 suggests its role during this process.

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Year:  1993        PMID： 8484778     DOI： 10.1006/bbrc.1993.1473

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  8 in total

Review 1.  Transcriptional control of terminal nephron differentiation.

Authors:  Samir S El-Dahr; Karam Aboudehen; Zubaida Saifudeen
Journal:  Am J Physiol Renal Physiol       Date:  2008-02-20

2.  The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism.

Authors:  Joseph B Moore; John Zhao; Matthew C L Keith; Alok R Amraotkar; Marcin Wysoczynski; Kyung U Hong; Roberto Bolli
Journal:  Stem Cells       Date:  2016-09-01       Impact factor: 6.277

3.  Epigenetically modified cardiac mesenchymal stromal cells limit myocardial fibrosis and promote functional recovery in a model of chronic ischemic cardiomyopathy.

Authors:  Joseph B Moore; Xian-Liang Tang; John Zhao; Annalara G Fischer; Wen-Jian Wu; Shizuka Uchida; Anna M Gumpert; Heather Stowers; Marcin Wysoczynski; Roberto Bolli
Journal:  Basic Res Cardiol       Date:  2018-11-16       Impact factor: 17.165

4.  Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

Authors:  C Missero; E Calautti; R Eckner; J Chin; L H Tsai; D M Livingston; G P Dotto
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-06       Impact factor: 11.205

5.  p53-dependent activation of the mouse MCK gene promoter: identification of a novel p53-responsive sequence and evidence for cooperation between distinct p53 binding sites.

Authors:  P Jackson; M Shield; J Buskin; S Hawkes; M Reed; K Perrem; S D Hauschka; A Braithwaite
Journal:  Gene Expr       Date:  1995

6.  The Satellite Cell Niche Regulates the Balance between Myoblast Differentiation and Self-Renewal via p53.

Authors:  Valentina Flamini; Rachel S Ghadiali; Philipp Antczak; Amy Rothwell; Jeremy E Turnbull; Addolorata Pisconti
Journal:  Stem Cell Reports       Date:  2018-02-08       Impact factor: 7.765

7.  Malat1 as an evolutionarily conserved lncRNA, plays a positive role in regulating proliferation and maintaining undifferentiated status of early-stage hematopoietic cells.

Authors:  Xian-Yong Ma; Jian-Hui Wang; Jing-Lan Wang; Charles X Ma; Xiao-Chun Wang; Feng-Song Liu
Journal:  BMC Genomics       Date:  2015-09-03       Impact factor: 3.969

Review 8.  P53 functional abnormality in mesenchymal stem cells promotes osteosarcoma development.

Authors:  T Velletri; N Xie; Y Wang; Y Huang; Q Yang; X Chen; Q Chen; P Shou; Y Gan; G Cao; G Melino; Y Shi
Journal:  Cell Death Dis       Date:  2016-01-21       Impact factor: 8.469
  8 in total

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