Literature DB >> 8483938

Mapping the determinants of human immunodeficiency virus 2 for infectivity, replication efficiency, and cytopathicity.

R Talbott1, G Kraus, D Looney, F Wong-Staal.   

Abstract

Human immunodeficiency virus 2 (HIV-2) ISY and the newly derived HIV-2KR are infectious molecular clones that yield viruses differing markedly in their abilities to infect and/or induce syncytia in various T- and monocytoid-cell lines. Chimeric viruses were constructed from these two viral genomes to localize the genetic determinants of some of these properties. Envelope sequences, particularly those spanning the CD4 binding site, appear to be critical for the ability of HIV-2KR to infect MOLT-4 clone 8 and SupT1 cells and to efficiently infect the H9 cell line. On the other hand, multiple determinants may contribute to cytopathicity (gp41 and nef) in H9 cells and replication efficiency in monocytic (THP-1) cells.

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Year:  1993        PMID： 8483938      PMCID： PMC46479          DOI： 10.1073/pnas.90.9.4226

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  23 in total

1.  Human infection by genetically diverse SIVSM-related HIV-2 in west Africa.

Authors:  F Gao; L Yue; A T White; P G Pappas; J Barchue; A P Hanson; B M Greene; P M Sharp; G M Shaw; B H Hahn
Journal:  Nature       Date:  1992-08-06       Impact factor: 49.962

2.  Viral DNA and mRNA expression correlate with the stage of human immunodeficiency virus (HIV) type 1 infection in humans: evidence for viral replication in all stages of HIV disease.

Authors:  N L Michael; M Vahey; D S Burke; R R Redfield
Journal:  J Virol       Date:  1992-01       Impact factor: 5.103

3.  Human immunodeficiency virus type 1 negative factor is a transcriptional silencer.

Authors:  T M Niederman; B J Thielan; L Ratner
Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

4.  Biologically diverse molecular variants within a single HIV-1 isolate.

Authors:  A G Fisher; B Ensoli; D Looney; A Rose; R C Gallo; M S Saag; G M Shaw; B H Hahn; F Wong-Staal
Journal:  Nature       Date:  1988-08-04       Impact factor: 49.962

5.  Nef proteins of the human immunodeficiency viruses (HIV-1 and HIV-2) and simian immunodeficiency virus (SIV) are structurally similar to leucine zipper transcriptional activation factors.

Authors:  K P Samuel; D R Hodge; Y M Chen; T S Papas
Journal:  AIDS Res Hum Retroviruses       Date:  1991-08       Impact factor: 2.205

6.  Human immunodeficiency virus type 1 envelope gene structure and diversity in vivo and after cocultivation in vitro.

Authors:  K Kusumi; B Conway; S Cunningham; A Berson; C Evans; A K Iversen; D Colvin; M V Gallo; S Coutre; E G Shpaer
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103

7.  Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population.

Authors:  H Schuitemaker; M Koot; N A Kootstra; M W Dercksen; R E de Goede; R P van Steenwijk; J M Lange; J K Schattenkerk; F Miedema; M Tersmette
Journal:  J Virol       Date:  1992-03       Impact factor: 5.103

8.  Human immunodeficiency virus type 2 envelope glycoprotein: differential CD4 interactions of soluble gp120 versus the assembled envelope complex.

Authors:  M J Mulligan; G D Ritter; M A Chaikin; G V Yamshchikov; P Kumar; B H Hahn; R W Sweet; R W Compans
Journal:  Virology       Date:  1992-03       Impact factor: 3.616

9.  Study of the interaction of HIV-1 and HIV-2 envelope glycoproteins with the CD4 receptor and role of N-glycans.

Authors:  E Bahraoui; A Benjouad; D Guetard; H Kolbe; J C Gluckman; L Montagnier
Journal:  AIDS Res Hum Retroviruses       Date:  1992-05       Impact factor: 2.205

10.  Molecular and biological characterization of a replication competent human immunodeficiency type 2 (HIV-2) proviral clone.

Authors:  G Franchini; K A Fargnoli; F Giombini; L Jagodzinski; A De Rossi; M Bosch; G Biberfeld; E M Fenyo; J Albert; R C Gallo
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205
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  13 in total

1.  IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation.

Authors:  Dominik Hotter; Matteo Bosso; Kasper L Jønsson; Christian Krapp; Christina M Stürzel; Atze Das; Elisabeth Littwitz-Salomon; Ben Berkhout; Alina Russ; Sabine Wittmann; Thomas Gramberg; Yue Zheng; Laura J Martins; Vicente Planelles; Martin R Jakobsen; Beatrice H Hahn; Ulf Dittmer; Daniel Sauter; Frank Kirchhoff
Journal:  Cell Host Microbe       Date:  2019-06-04       Impact factor: 21.023

2.  The replicative fitness of primary human immunodeficiency virus type 1 (HIV-1) group M, HIV-1 group O, and HIV-2 isolates.

Authors:  Kevin K Ariën; Awet Abraha; Miguel E Quiñones-Mateu; Luc Kestens; Guido Vanham; Eric J Arts
Journal:  J Virol       Date:  2005-07       Impact factor: 5.103

Review 3.  Development of HIV vectors for anti-HIV gene therapy.

Authors:  E Poeschla; P Corbeau; F Wong-Staal
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-15       Impact factor: 11.205

4.  Biological signature characteristics of primary isolates from human immunodeficiency virus type 1 group O in ex vivo human tonsil histocultures.

Authors:  Silvia Geuenich; Lars Kaderali; Ina Allespach; Serkan Sertel; Oliver T Keppler
Journal:  J Virol       Date:  2009-08-12       Impact factor: 5.103

5.  Genetic diversity of human immunodeficiency virus type 2: evidence for distinct sequence subtypes with differences in virus biology.

Authors:  F Gao; L Yue; D L Robertson; S C Hill; H Hui; R J Biggar; A E Neequaye; T M Whelan; D D Ho; G M Shaw
Journal:  J Virol       Date:  1994-11       Impact factor: 5.103

6.  Identification of a human immunodeficiency virus type 2 (HIV-2) encapsidation determinant and transduction of nondividing human cells by HIV-2-based lentivirus vectors.

Authors:  E Poeschla; J Gilbert; X Li; S Huang; A Ho; F Wong-Staal
Journal:  J Virol       Date:  1998-08       Impact factor: 5.103

7.  Tat-independent replication of human immunodeficiency viruses.

Authors:  L Luznik; G Kraus; J Guatelli; D Richman; F Wong-Staal
Journal:  J Clin Invest       Date:  1995-01       Impact factor: 14.808

8.  An infectious chimeric human immunodeficiency virus type 2 (HIV-2) expressing the HIV-1 principal neutralizing determinant.

Authors:  M Mamounas; D J Looney; R Talbott; F Wong-Staal
Journal:  J Virol       Date:  1995-10       Impact factor: 5.103

9.  Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants.

Authors:  T R Reddy; G Kraus; O Yamada; D J Looney; M Suhasini; F Wong-Staal
Journal:  J Virol       Date:  1995-06       Impact factor: 5.103

10.  Functional analysis of Vif protein shows less restriction of human immunodeficiency virus type 2 by APOBEC3G.

Authors:  Ana Clara Ribeiro; Alexandra Maia e Silva; Mariana Santa-Marta; Ana Pombo; José Moniz-Pereira; Joao Goncalves; Isabel Barahona
Journal:  J Virol       Date:  2005-01       Impact factor: 5.103
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