Literature DB >> 848362

Cardaic arrhythmias in chloral hydrate poisoning.

A Gustafson, S E Svensson, L Ugander.   

Abstract

In three patients admitted to hospital after ingestion of an overdose of chloral hydrate, the ECG showed supreventricular and ventricular tachyarrhythmias. The possible mechanism for the arrhythmias may be an enhanced automaticity of supraventricular and ventricular pacemaker cells caused by metabolites of chloral hydrate. The ventricular arrhythmia responded to i.v. treatment with lignocaine in one patient, and to phenytoin in another in whom lignocaine failed to restore a normal sinus rhythm.

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Year:  1977        PMID: 848362     DOI: 10.1111/j.0954-6820.1977.tb15687.x

Source DB:  PubMed          Journal:  Acta Med Scand        ISSN: 0001-6101


  4 in total

Review 1.  Therapeutic assessment of chloral hydrate premedication for pediatric dentistry.

Authors:  P A Moore
Journal:  Anesth Prog       Date:  1984 Sep-Oct

2.  Cardiac arrhythmias due to chloral hydrate poisoning.

Authors:  H M Wiseman; G Hampel
Journal:  Br Med J       Date:  1978-09-30

Review 3.  QT-interval prolonging drugs: mechanisms and clinical relevance of their arrhythmogenic hazards.

Authors:  M Zehender; S Hohnloser; H Just
Journal:  Cardiovasc Drugs Ther       Date:  1991-04       Impact factor: 3.727

4.  Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker.

Authors:  Shaik Karimulla Shakeer; Babji Kalapati; Suad Abdullah Al Abri; Mujahid Al Busaidi
Journal:  Oman Med J       Date:  2019-05
  4 in total

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