An eleven-year follow-up on 64 subjects with M-components.

In a medical health survey in 1964 of 6995 subjects, 64 persons with M-components were detected by serum electrophoresis. One had clearcut signs of myelomatosis and one had lymphatic leukemia. Eleven years later 27 persons had died. In the case with lymphatic leukemia the disease had changed after 6 years into a myelomatosis. One person died after 9 years from a malignant lymphoma. Among the 37 persons still alive there seemed to be no clustering of diseases. The whole series represents an observation time of 487 years. No more myelomas or lymphomas were detected. One M-component had disappeared.