Literature DB >> 8483221

The effect of gastric augmentation on bladder function.

A Atala1, S B Bauer, W H Hendren, A B Retik.   

Abstract

Gastrocystoplasty was performed in 29 female and 14 male patients 1 to 23 years old (average age 11 years). Urodynamic studies were completed in 20 patients preoperatively and within 6 months postoperatively. When postoperative studies were compared with the preoperative evaluation, it was noted that overall capacity increased an average of 220% (range 20 to 750%). Compliance also improved dramatically postoperatively. Bladder pressures increased from a mean volume of 34% of capacity preoperatively to 73% of the post-augment capacity. The average maximum filling pressure decreased by 32%, from 57 to 39 cm. water. Uninhibited contractions resolved completely in 6 of 10 patients who had them preoperatively. No one had uninhibited contractions postoperatively. Cyclical contractions of the stomach segment not exceeding 50 cm. water developed in 6 patients. The gastric patch seems to be an adequate source for improving the dynamics of a poorly functioning detrusor muscle in most patients. When a diamond-shaped patch of stomach is harvested and added to the bladder a spherical configuration is created, enhancing the storage properties. This result is in sharp contrast to other bowel segments, which must be detubularized to produce a suitable reservoir. The long-term effects of gastric augmentation remain to be determined.

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Year:  1993        PMID: 8483221     DOI: 10.1016/s0022-5347(17)36307-3

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  6 in total

1.  The use of seromuscular tapered ileal tube in ureteral replacement: an experimental model.

Authors:  Mahmoud Ezzat Ibrahim; Mohamed M Ezzat; Wail M Ezzat
Journal:  Int Urol Nephrol       Date:  2009-12-15       Impact factor: 2.370

Review 2.  Bladder biomechanics and the use of scaffolds for regenerative medicine in the urinary bladder.

Authors:  Fatemeh Ajalloueian; Greg Lemon; Jöns Hilborn; Ioannis S Chronakis; Magdalena Fossum
Journal:  Nat Rev Urol       Date:  2018-02-13       Impact factor: 14.432

Review 3.  Regenerative medicine as applied to general surgery.

Authors:  Giuseppe Orlando; Kathryn J Wood; Paolo De Coppi; Pedro M Baptista; Kyle W Binder; Khalil N Bitar; Christopher Breuer; Luke Burnett; George Christ; Alan Farney; Marina Figliuzzi; James H Holmes; Kenneth Koch; Paolo Macchiarini; Sayed-Hadi Mirmalek Sani; Emmanuel Opara; Andrea Remuzzi; Jeffrey Rogers; Justin M Saul; Dror Seliktar; Keren Shapira-Schweitzer; Tom Smith; Daniel Solomon; Mark Van Dyke; James J Yoo; Yuanyuan Zhang; Anthony Atala; Robert J Stratta; Shay Soker
Journal:  Ann Surg       Date:  2012-05       Impact factor: 12.969

Review 4.  Bioengineering Approaches for Bladder Regeneration.

Authors:  Ángel Serrano-Aroca; César David Vera-Donoso; Victoria Moreno-Manzano
Journal:  Int J Mol Sci       Date:  2018-06-17       Impact factor: 5.923

5.  New era in health care: tissue engineering.

Authors:  S Parveen; K Krishnakumar; Sk Sahoo
Journal:  J Stem Cells Regen Med       Date:  2006-12-26

6.  Generation of bladder urothelium from human pluripotent stem cells under chemically defined serum- and feeder-free system.

Authors:  Minyong Kang; Hyeon Hoe Kim; Yong-Mahn Han
Journal:  Int J Mol Sci       Date:  2014-04-25       Impact factor: 5.923

  6 in total

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