Intraluminal pancreatic candidiasis presenting as recurrent pancreatitis.

An 88-year-old man with closely spaced attacks of acute pancreatitis who was found to have ductal changes of chronic pancreatitis with multiple noncalcified intraluminal filling defects during endoscopic retrograde pancreatography is presented. These defects proved to be fungus balls made up of Candida albicans. He was treated with longitudinal pancreaticojejunostomy and oral fluconazole and has since remained recurrence free (30 months). It is suggested that Candida superinfection may occur in a chronically dilated pancreatic duct and may contribute to symptomatic recurrent inflammation of the pancreas.