Literature DB >> 8482075

Antioxidant properties of di- and polyamines.

B Matkovics1, V Kecskemeti, S I Varga, Z Novak, Z Kertesz.   

Abstract

1. One diamine, putrescine and two polyamines, spermidine and spermine (PAs) of different concentrations, were processed through antioxidant systems in order to study their antioxidant effects. The systems investigated were as follows. 2. "Oxidative stress" was induced in RBCs to investigate filtration parameters, the effect of reduced glutathione (GSH) and the change in lipid peroxidation (LP) superoxide dismutase (SOD) activities. 3. Initiated LP-decreasing characteristics of the substances were studied in pig brain homogenate. 4. The LP-decreasing effect of these PAs were studied in guinea-pig heart tissue homogenate perfused with Tyrode solution, stimulated, and then perfused by the Langendorff method. 5. In all three tests, the antioxidant characteristics of PAs were unambiguously proved.

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Year:  1993        PMID： 8482075     DOI： 10.1016/0305-0491(93)90269-b

Source DB:  PubMed          Journal:  Comp Biochem Physiol B        ISSN： 0305-0491


  8 in total

1.  Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to 1,3-bis-(2-chloroethyl)-N-nitrosourea.

Authors:  C A Mackintosh; A E Pegg
Journal:  Biochem J       Date:  2000-10-15       Impact factor: 3.857

2.  Radiation protection following nuclear power accidents: a survey of putative mechanisms involved in the radioprotective actions of taurine during and after radiation exposure.

Authors:  Olav Albert Christophersen
Journal:  Microb Ecol Health Dis       Date:  2012-02-01

3.  Studies on the antiperoxide and antihaemolytic action of polyamines using human erythrocytes.

Authors:  C Chetan; A Prabhu; V D'Souza; S B Rao
Journal:  Indian J Clin Biochem       Date:  2000-08

4.  Hydroxyl radical scavenging and singlet oxygen quenching properties of polyamines.

Authors:  Kumuda C Das; Hara P Misra
Journal:  Mol Cell Biochem       Date:  2004-07       Impact factor: 3.396

5.  Spermine partially normalizes in vivo antioxidant defense potential in certain brain regions in transiently hypoperfused rat brain.

Authors:  R Farbiszewski; A Bielawska; M Szymanska; E Skrzydlewska
Journal:  Neurochem Res       Date:  1996-12       Impact factor: 3.996

6.  Protective effect of spermine on DNA exposed to oxidative stress.

Authors:  C Muscari; C Guarnieri; C Stefanelli; A Giaccari; C M Caldarera
Journal:  Mol Cell Biochem       Date:  1995-03-23       Impact factor: 3.396

7.  Investigation of indolglyoxamide and indolacetamide analogues of polyamines as antimalarial and antitrypanosomal agents.

Authors:  Jiayi Wang; Marcel Kaiser; Brent R Copp
Journal:  Mar Drugs       Date:  2014-05-28       Impact factor: 5.118

8.  A Comparative Metabolomic Analysis Reveals the Nutritional and Therapeutic Potential of Grains of the Traditional Rice Variety Mappillai Samba.

Authors:  Veera Ranjani Rajagopalan; Sudha Manickam; Raveendran Muthurajan
Journal:  Plants (Basel)       Date:  2022-02-18
  8 in total

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