| Literature DB >> 8481649 |
Y Tomer1, D Buskila, Y Shoenfeld.
Abstract
Systemic lupus erythematosus (SLE) is characterized by a panoply of autoantibodies (more than 50). Some of them are more prevalent (anti-ds DNA > 80%) while others are less frequently detected, but highly specific for SLE (anti-Sm, 20%). In this review we will discuss the clinical significance of anti-RNP, anti-Ro, anti-La and anti-phospholipid antibodies. We will also summarize the clinical and experimental evidence for the pathogenic role attributed to each one of these antibodies.Entities:
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Year: 1993 PMID： 8481649 DOI： 10.1159/000236429
Source DB: PubMed Journal: Int Arch Allergy Immunol ISSN： 1018-2438 Impact factor: 2.749