Literature DB >> 8480826

Clinical course of alcoholism in 636 male inpatients.

M A Schuckit1, T L Smith, R Anthenelli, M Irwin.   

Abstract

OBJECTIVE: This study was undertaken to determine the relative order of appearance of symptoms in alcohol dependence.
METHOD: The age at which 21 alcohol-related major life events first occurred was investigated in 636 male alcohol-dependent inpatients through a standardized, structured personal interview with each subject and at least one resource person.
RESULTS: A general pattern of first occurrence of these events was observed. Heavy drinking escalated further when the subjects were in their late 20s, followed by evidence of interference with functioning in multiple life areas in the early 30s, a subsequent perception of loss of control, and then an intensification of social and job-related problems, along with evidence of deterioration in body systems, in the mid- to late 30s. Similar patterns of problems emerged when the alcoholic subjects were divided into subgroups based on onset of alcohol dependence before or after age 30, presence or absence of a family history of alcoholism, and presence or absence of additional psychiatric disorders.
CONCLUSIONS: These data indicate that there is a typical progression of events related to alcohol dependence. This information can be useful for clinicians in their work with patients and for teachers and researchers as well.

Entities:  

Mesh:

Year:  1993        PMID: 8480826     DOI: 10.1176/ajp.150.5.786

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  13 in total

1.  Consequences of an adolescent onset and persistent course of alcohol dependence in men: adolescent risk factors and adult outcomes.

Authors:  Brian M Hicks; William G Iacono; Matt McGue
Journal:  Alcohol Clin Exp Res       Date:  2010-02-24       Impact factor: 3.455

2.  Clinical characteristics of alcohol combined with other substance use disorders in an American Indian community sample.

Authors:  David A Gilder; Gina M Stouffer; Philip Lau; Cindy L Ehlers
Journal:  Drug Alcohol Depend       Date:  2016-02-08       Impact factor: 4.492

3.  Does Neighborhood Alcohol Availability Moderate the Impact of Familial Liability and Marital Status on Risk for Alcohol Use Disorders? A Swedish National Study.

Authors:  Kenneth S Kendler; Sara Larsson Lönn; Katherine J Karriker-Jaffe; Jessica E Salvatore; Jan Sundquist; Kristina Sundquist
Journal:  J Stud Alcohol Drugs       Date:  2020-11       Impact factor: 2.582

4.  Age at regular drinking, clinical course, and heritability of alcohol dependence in the San Francisco family study: a gender analysis.

Authors:  Cindy L Ehlers; Ian R Gizer; Cassandra Vieten; Allison Gilder; David A Gilder; Gina M Stouffer; Philip Lau; Kirk C Wilhelmsen
Journal:  Am J Addict       Date:  2010 Mar-Apr

5.  Clinical course of alcohol dependence.

Authors:  S K Mattoo; D Basu
Journal:  Indian J Psychiatry       Date:  1997-10       Impact factor: 1.759

6.  Temporary parental separation at birth and substance use disorder in adulthood. A long-term follow-up of the Finnish Christmas Seal Home Children.

Authors:  Juha Veijola; Esa Läärä; Matti Joukamaa; Matti Isohanni; Helinä Hakko; Marianne Haapea; Sami Pirkola; Pirjo Mäki
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2007-10-24       Impact factor: 4.328

7.  The clinical course of alcoholism in Trinidad and Tobago.

Authors:  L Karelia Montane-Jaime; Samuel Shafe; Roma Joseph; Shelley Moore; David A Gilder; Helene Crooks; Celia Ramcharan; Cindy L Ehlers
Journal:  J Stud Alcohol Drugs       Date:  2008-11       Impact factor: 2.582

8.  The clinical course of DSM-5 alcohol use disorders in young adult native and Mexican Americans.

Authors:  Cindy L Ehlers; Gina M Stouffer; Linda Corey; David A Gilder
Journal:  Am J Addict       Date:  2015-09-08

9.  Common genetic substrates of alcohol and substance use disorder severity revealed by pleiotropy detection against GWAS catalog in two populations.

Authors:  Qian Peng; Kirk C Wilhelmsen; Cindy L Ehlers
Journal:  Addict Biol       Date:  2020-02-06       Impact factor: 4.280

10.  Long tracks of homozygosity predict the severity of alcohol use disorders in an American Indian population.

Authors:  Qian Peng; Cindy L Ehlers
Journal:  Mol Psychiatry       Date:  2021-01-04       Impact factor: 13.437

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.