Literature DB >> 8479908

A chicken RAD51 homologue is expressed at high levels in lymphoid and reproductive organs.

O Bezzubova1, A Shinohara, R G Mueller, H Ogawa, J M Buerstedde.   

Abstract

Comparisons of the amino acid sequences of three yeast RecA-like proteins, Rad51 and DMC1 from S.cerevisiae and Rad51 from S.pombe, revealed several highly conserved regions. Degenerated oligonucleotides encoding two of these regions were used for the polymerase chain reaction to clone a chicken RecA-like gene. The encoded protein shares 68% and 49% identical amino acids with the Rad51 and DMC1 proteins. The strong sequence conservation between the yeast and chicken genes indicates that RecA homologues are conserved throughout evolution from prokaryotes to higher eukaryotes. High expression of the chicken Rad51 gene was found within the organs of lymphoid and germ cell development suggesting its involvement in lymphoid and meiotic recombination.

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Year:  1993        PMID： 8479908      PMCID： PMC309365          DOI： 10.1093/nar/21.7.1577

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  24 in total

1.  A hyperconversion mechanism generates the chicken light chain preimmune repertoire.

Authors:  C A Reynaud; V Anquez; H Grimal; J C Weill
Journal:  Cell       Date:  1987-02-13       Impact factor: 41.582

2.  Somatic diversification of the chicken immunoglobulin light chain gene is limited to the rearranged variable gene segment.

Authors:  C B Thompson; P E Neiman
Journal:  Cell       Date:  1987-02-13       Impact factor: 41.582

3.  The molecular basis of antibody formation: a paradox.

Authors:  W J Dreyer; J C Bennett
Journal:  Proc Natl Acad Sci U S A       Date:  1965-09       Impact factor: 11.205

Review 4.  Somatic generation of antibody diversity.

Authors:  S Tonegawa
Journal:  Nature       Date:  1983-04-14       Impact factor: 49.962

5.  A single rearrangement event generates most of the chicken immunoglobulin light chain diversity.

Authors:  C A Reynaud; V Anquez; A Dahan; J C Weill
Journal:  Cell       Date:  1985-02       Impact factor: 41.582

6.  Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes.

Authors:  M Kozak
Journal:  Cell       Date:  1986-01-31       Impact factor: 41.582

7.  Genetic control of diploid recovery after gamma-irradiation in the yeast Saccharomyces cerevisiae.

Authors:  T Saeki; I Machida; S Nakai
Journal:  Mutat Res       Date:  1980-12       Impact factor: 2.433

8.  A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae.

Authors:  R Kostriken; J N Strathern; A J Klar; J B Hicks; F Heffron
Journal:  Cell       Date:  1983-11       Impact factor: 41.582

9.  Repair of interstrand cross-links in DNA of Saccharomyces cerevisiae requires two systems for DNA repair: the RAD3 system and the RAD51 system.

Authors:  W J Jachymczyk; R C von Borstel; M R Mowat; P J Hastings
Journal:  Mol Gen Genet       Date:  1981

10.  Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

Authors:  J E Walker; M Saraste; M J Runswick; N J Gay
Journal:  EMBO J       Date:  1982       Impact factor: 11.598
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  38 in total

Review 1.  Homologous DNA recombination in vertebrate cells.

Authors:  E Sonoda; M Takata; Y M Yamashita; C Morrison; S Takeda
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-17       Impact factor: 11.205

2.  Homomeric interaction of the mouse Rad52 protein.

Authors:  L Krejci; B Thomsen; M Duno; O Westergaard; C Bendixen
Journal:  Mol Biol Rep       Date:  2000-03       Impact factor: 2.316

3.  Genetic and cytological characterization of the RecA-homologous proteins Rad51 and Dmc1 of Schizosaccharomyces pombe.

Authors:  Alexandra L Grishchuk; Rolf Kraehenbuehl; Monika Molnar; Oliver Fleck; Juerg Kohli
Journal:  Curr Genet       Date:  2003-08-29       Impact factor: 3.886

4.  Targeted disruption of the Rad51 gene leads to lethality in embryonic mice.

Authors:  T Tsuzuki; Y Fujii; K Sakumi; Y Tominaga; K Nakao; M Sekiguchi; A Matsushiro; Y Yoshimura
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

5.  Distribution of the Rad51 recombinase in human and mouse spermatocytes.

Authors:  A L Barlow; F E Benson; S C West; M A Hultén
Journal:  EMBO J       Date:  1997-09-01       Impact factor: 11.598

6.  The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination.

Authors:  R Kooistra; K Vreeken; J B Zonneveld; A de Jong; J C Eeken; C J Osgood; J M Buerstedde; P H Lohman; A Pastink
Journal:  Mol Cell Biol       Date:  1997-10       Impact factor: 4.272

7.  The human Rad51 protein: polarity of strand transfer and stimulation by hRP-A.

Authors:  P Baumann; S C West
Journal:  EMBO J       Date:  1997-09-01       Impact factor: 11.598

8.  Identification of a chicken RAD52 homologue suggests conservation of the RAD52 recombination pathway throughout the evolution of higher eukaryotes.

Authors:  O Y Bezzubova; H Schmidt; K Ostermann; W D Heyer; J M Buerstedde
Journal:  Nucleic Acids Res       Date:  1993-12-25       Impact factor: 16.971

9.  Identification and characterization of the RAD51 gene from the ciliate Tetrahymena thermophila.

Authors:  C Campbell; D P Romero
Journal:  Nucleic Acids Res       Date:  1998-07-01       Impact factor: 16.971

10.  The Arabidopsis AtRAD51 gene is dispensable for vegetative development but required for meiosis.

Authors:  Wuxing Li; Changbin Chen; Ullrich Markmann-Mulisch; Ljudmilla Timofejeva; Elmon Schmelzer; Hong Ma; Bernd Reiss
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-12       Impact factor: 11.205
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