Literature DB >> 8478907

N-(1-methyl-5-indolyl)-N'-(3-pyridyl)urea hydrochloride: the first selective 5-HT1C receptor antagonist.

I T Forbes1, G A Kennett, A Gadre, P Ham, C J Hayward, R T Martin, M Thompson, M D Wood, G S Baxter, A Glen.   

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Year:  1993        PMID: 8478907     DOI: 10.1021/jm00060a019

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  11 in total

1.  Effect of SB 200646A, a 5-HT2C/5-HT2B receptor antagonist, in two conflict models of anxiety.

Authors:  G A Kennett; F Bailey; D C Piper; T P Blackburn
Journal:  Psychopharmacology (Berl)       Date:  1995-03       Impact factor: 4.530

2.  Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in human neocortex slices: involvement of 5-HT(2C) and 5-HT(1A) receptors.

Authors:  G Maura; M Marcoli; O Pepicelli; C Rosu; C Viola; M Raiteri
Journal:  Br J Pharmacol       Date:  2000-08       Impact factor: 8.739

3.  Predicted structures and dynamics for agonists and antagonists bound to serotonin 5-HT2B and 5-HT2C receptors.

Authors:  Soo-Kyung Kim; Youyong Li; Ravinder Abrol; Jiyoung Heo; William A Goddard
Journal:  J Chem Inf Model       Date:  2011-02-07       Impact factor: 4.956

4.  Further characterization of 5-hydroxytryptamine receptors (putative 5-HT2B) in rat stomach fundus longitudinal muscle.

Authors:  G S Baxter; O E Murphy; T P Blackburn
Journal:  Br J Pharmacol       Date:  1994-05       Impact factor: 8.739

5.  In vitro and in vivo profile of SB 206553, a potent 5-HT2C/5-HT2B receptor antagonist with anxiolytic-like properties.

Authors:  G A Kennett; M D Wood; F Bright; J Cilia; D C Piper; T Gager; D Thomas; G S Baxter; I T Forbes; P Ham; T P Blackburn
Journal:  Br J Pharmacol       Date:  1996-02       Impact factor: 8.739

6.  The pharmacology and distribution of human 5-hydroxytryptamine2B (5-HT2B) receptor gene products: comparison with 5-HT2A and 5-HT2C receptors.

Authors:  D W Bonhaus; C Bach; A DeSouza; F H Salazar; B D Matsuoka; P Zuppan; H W Chan; R M Eglen
Journal:  Br J Pharmacol       Date:  1995-06       Impact factor: 8.739

7.  In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonist.

Authors:  G A Kennett; M D Wood; A Glen; S Grewal; I Forbes; A Gadre; T P Blackburn
Journal:  Br J Pharmacol       Date:  1994-03       Impact factor: 8.739

8.  Mediation by 5-hydroxytryptamine2B receptors of endothelium-dependent relaxation in rat jugular vein.

Authors:  E S Ellis; C Byrne; O E Murphy; N S Tilford; G S Baxter
Journal:  Br J Pharmacol       Date:  1995-01       Impact factor: 8.739

9.  Effects of the 5-HT2B receptor agonist, BW 723C86, on three rat models of anxiety.

Authors:  G A Kennett; F Bright; B Trail; G S Baxter; T P Blackburn
Journal:  Br J Pharmacol       Date:  1996-04       Impact factor: 8.739

10.  In vivo Schild regression analyses using nonselective 5-HT2C receptor antagonists in a rat operant behavioral assay.

Authors:  Ellen A Walker; Edward K Brown; Steven N Sterious
Journal:  Psychopharmacology (Berl)       Date:  2007-04-01       Impact factor: 4.415

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