PURPOSE: This report describes a previously unreported clinical phenomenon that occurs in some patients after completion of combination chemotherapy. METHODS AND RESULTS: Eight case reports are presented. Affected patients developed a syndrome of myalgias/arthralgias within several months of completing cyclophosphamide/fluorouracil (5FU)-containing adjuvant combination chemotherapy for breast cancer. These symptoms did not appear to be related to cancer recurrence or any common rheumatologic disorder. The syndrome generally resolved over several months. CONCLUSION: Postchemotherapy rheumatism is a syndrome of myalgias/arthralgias that usually develops 1 to 3 months after completion of adjuvant chemotherapy. Recognition of this syndrome can limit the need for extensive work-ups to exclude recurrent breast cancer or inflammatory rheumatologic diseases.
PURPOSE: This report describes a previously unreported clinical phenomenon that occurs in some patients after completion of combination chemotherapy. METHODS AND RESULTS: Eight case reports are presented. Affected patients developed a syndrome of myalgias/arthralgias within several months of completing cyclophosphamide/fluorouracil (5FU)-containing adjuvant combination chemotherapy for breast cancer. These symptoms did not appear to be related to cancer recurrence or any common rheumatologic disorder. The syndrome generally resolved over several months. CONCLUSION: Postchemotherapy rheumatism is a syndrome of myalgias/arthralgias that usually develops 1 to 3 months after completion of adjuvant chemotherapy. Recognition of this syndrome can limit the need for extensive work-ups to exclude recurrent breast cancer or inflammatory rheumatologic diseases.
Authors: Ting Bao; Andrew Seidman; Qing Li; Christina Seluzicki; Victoria Blinder; Salimah H Meghani; John T Farrar; Jun J Mao Journal: Breast Cancer Res Treat Date: 2018-01-19 Impact factor: 4.872
Authors: N Lynn Henry; Jon T Giles; Dennis Ang; Monika Mohan; Dina Dadabhoy; Jason Robarge; Jill Hayden; Suzanne Lemler; Karineh Shahverdi; Penny Powers; Lang Li; David Flockhart; Vered Stearns; Daniel F Hayes; Anna Maria Storniolo; Daniel J Clauw Journal: Breast Cancer Res Treat Date: 2007-10-06 Impact factor: 4.872