Literature DB >> 8478008

Partial physical map of human chromosome 21 from fibroblast and lymphocyte DNA.

N Crété1, J M Delabar, Z Rahmani, M L Yaspo, J Kraus, A Marks, P M Sinet, N Créau-Goldberg.   

Abstract

A partial physical map of the human chromosome 21 including 26 genes and anonymous sequences was established by pulsed-field gel electrophoresis analysis of restriction fragments obtained from lymphocyte and fibroblast DNAs. The sizes of the restriction fragments obtained by total digestion with eight different enzymes were compared in these two tissues. Differences resulting from the variations in the methylation state of the restriction sites were frequently observed. These differences and partial digestions were used to estimate the order and the distances between genes and sequences. Six linkage groups were defined: D21S13-D21S16, D21S1-D21S11, D21S65-D21S17, (D21S55,ERG)-ETS2, BCEI-D21S19-D21S42-D21S113-CBS-CRYA1, and COL6A2-S100B. For six intergenic distances the resolution of previous maps was significantly increased.

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Year:  1993        PMID： 8478008     DOI： 10.1007/bf00218265

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  39 in total

1.  Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome.

Authors:  Z Rahmani; J L Blouin; N Creau-Goldberg; P C Watkins; J F Mattei; M Poissonnier; M Prieur; Z Chettouh; A Nicole; A Aurias
Journal:  Proc Natl Acad Sci U S A       Date:  1989-08       Impact factor: 11.205

2.  Report of the Second International Workshop on Human Chromosome 21 mapping.

Authors:  D Patterson
Journal:  Cytogenet Cell Genet       Date:  1991

3.  The pericentromeric 21 DNA marker pGSM21 (D21S13) contains an expressed HTF island.

Authors:  P Stinissen; W Van Hul; G Van Camp; H Backhovens; A Wehnert; A Vandenberghe; C Van Broeckhoven
Journal:  Genomics       Date:  1990-05       Impact factor: 5.736

4.  Cloning and chromosomal localization of human genes encoding the three chains of type VI collagen.

Authors:  D Weil; M G Mattei; E Passage; V C N'Guyen; D Pribula-Conway; K Mann; R Deutzmann; R Timpl; M L Chu
Journal:  Am J Hum Genet       Date:  1988-03       Impact factor: 11.025

5.  Isolation and mapping of a polymorphic DNA sequence (pMCT15) on chromosome 21 [D21S113].

Authors:  Y Nakamura; M Carlson; K Krapcho; L Ballard; M Leppert; P O'Connell; G M Lathrop; J M Lalouel; R White
Journal:  Nucleic Acids Res       Date:  1988-10-25       Impact factor: 16.971

6.  Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder.

Authors:  P H St George-Hyslop; J L Haines; L A Farrer; R Polinsky; C Van Broeckhoven; A Goate; D R McLachlan; H Orr; A C Bruni; S Sorbi; I Rainero; J F Foncin; D Pollen; J M Cantu; R Tupler; N Voskresenskaya; R Mayeux; J Growden; V A Fried; R H Myers; L Nee; H Backhovens; J J Martin; M Rossor; M J Owen; M Mullan; M E Percy; H Karlinsky; S Rich; L Heston; M Montesi; M Mortilla; N Nacmias; J F Gusella; J A Hardy
Journal:  Nature       Date:  1990-09-13       Impact factor: 49.962

7.  The alpha-A-crystallin and cystathionine beta-synthase genes are physically very closely linked in proximal mouse chromosome 17.

Authors:  L Stubbs; J Kraus; H Lehrach
Journal:  Genomics       Date:  1990-06       Impact factor: 5.736

8.  erg, a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation.

Authors:  V N Rao; T S Papas; E S Reddy
Journal:  Science       Date:  1987-08-07       Impact factor: 47.728

9.  Cloning and screening with nanogram amounts of immunopurified mRNAs: cDNA cloning and chromosomal mapping of cystathionine beta-synthase and the beta subunit of propionyl-CoA carboxylase.

Authors:  J P Kraus; C L Williamson; F A Firgaira; T L Yang-Feng; M Münke; U Francke; L E Rosenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

10.  Human cytoplasmic superoxide dismutase cDNA clone: a probe for studying the molecular biology of Down syndrome.

Authors:  J Lieman-Hurwitz; N Dafni; V Lavie; Y Groner
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205
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  5 in total

1.  Identification of a second promoter in the human c-ets-2 proto-oncogene.

Authors:  A Bègue; P Crepieux; N Vu-Dac; A Hautefeuille; N Spruyt; V Laudet; D Stehelin
Journal:  Gene Expr       Date:  1997

2.  Physical structure of human chromosome 21: an analysis of YACs spanning 21q.

Authors:  H Ochman; L A Buckholtz
Journal:  Mamm Genome       Date:  1995-02       Impact factor: 2.957

3.  A high-resolution map of 1.6 Mb in the Down syndrome region: a new map between D21S55 and ETS2.

Authors:  P Gosset; N Crété; G Ait Ghezala; D Théophile; C Van Broeckhoven; C Vayssettes; P M Sinet; N Créau
Journal:  Mamm Genome       Date:  1995-02       Impact factor: 2.957

4.  Bacterial contig map of the 21q11 region associated with Alzheimer's disease and abnormal myelopoiesis in Down syndrome.

Authors:  J Groet; J H Ives; A P South; P R Baptista; T A Jones; M L Yaspo; H Lehrach; M C Potier; C Van Broeckhoven; D Nizetić
Journal:  Genome Res       Date:  1998-04       Impact factor: 9.043

5.  Variability of EWS chimaeric transcripts in Ewing tumours: a comparison of clinical and molecular data.

Authors:  A Zoubek; C Pfleiderer; M Salzer-Kuntschik; G Amann; R Windhager; F M Fink; E Koscielniak; O Delattre; S Strehl; P F Ambros
Journal:  Br J Cancer       Date:  1994-11       Impact factor: 7.640
  5 in total

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