| Literature DB >> 8477514 |
T Adachi1, M Saito, J Sasaki, Y Karasawa, H Araki, K Hanada, S Omura.
Abstract
(6R)-6-Hydroxy-, (6S)-6-hydroxy- and (18S)-18-hydroxyeburnamonines were obtained by microbial conversion of (-)-eburnamonine using Mucor circinelloides and Streptomyces violens. Their structures were determined by analyses of the mass, 1H- and 13C-NMR spectra. (-)-Eburnamonine and the three hydroxylated compounds showed cerebral protecting effects against potassium cyanide intoxication in mice.Entities:
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Year: 1993 PMID： 8477514 DOI： 10.1248/cpb.41.611
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645