OBJECTIVE: To test the effect of peritoneal fluid from infertile women with minimal or mild endometriosis on sperm movement characteristics in comparison with fertile and infertile women with no endometriosis. DESIGN: A prospective observer-blind trial. SETTING: Academic infertility department. SUBJECTS: 57 women undergoing diagnostic laparoscopy or laparoscopic sterilisation. MAIN OUTCOME MEASURES: Changes in sperm movement characteristics in semen samples provided during routine infertility investigation or from sperm donors. Computer assisted semen analysis (CASA) performed using a Celltrack-S system. RESULTS: Significant reductions in linearity (P < 0.05), amplitude of lateral head displacement (P < 0.01), straight line velocity (P < 0.01), and curvilinear velocity (P < 0.01) (but not percentage motility) were observed. CONCLUSIONS: Peritoneal fluid from women with minimal or mild endometriosis adversely effects sperm movement characteristics in comparison to fertile women.
OBJECTIVE: To test the effect of peritoneal fluid from infertilewomen with minimal or mild endometriosis on sperm movement characteristics in comparison with fertile and infertilewomen with no endometriosis. DESIGN: A prospective observer-blind trial. SETTING:Academic infertility department. SUBJECTS: 57 women undergoing diagnostic laparoscopy or laparoscopic sterilisation. MAIN OUTCOME MEASURES: Changes in sperm movement characteristics in semen samples provided during routine infertility investigation or from sperm donors. Computer assisted semen analysis (CASA) performed using a Celltrack-S system. RESULTS: Significant reductions in linearity (P < 0.05), amplitude of lateral head displacement (P < 0.01), straight line velocity (P < 0.01), and curvilinear velocity (P < 0.01) (but not percentage motility) were observed. CONCLUSIONS: Peritoneal fluid from women with minimal or mild endometriosis adversely effects sperm movement characteristics in comparison to fertile women.