| Literature DB >> 847470 |
Abstract
Formulas for estimating the probability that chimeric plasmids carried by disarmed hosts will become established in natural populations of bacteria are presented and their use illustrated with a series of realistic numerical examples. The implications of these a priori probability estimates for the problem of containment for recombinant DNA research is discussed.Mesh:
Substances:
Year: 1977 PMID: 847470 DOI: 10.1126/science.847470
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728