Literature DB >> 8473012

Interleukin-6 biosynthesis is increased by histamine in human B-cell and glioblastoma cell lines.

A Falus1.   

Abstract

An enhancing effect of histamine on the biosynthesis and gene expression of interleukin-6 (IL-6) by human cell lines, Epstein-Barr virus (EBV)-infected human B lymphoma line BMNH and the glioblastoma line SK-MG4 has been found. No similar effect of histamine has been detected on the IL-6 production by any other B-cell line, CESS or human peripheral monocytes. Histamine stimulates the IgM production of BMNH cells by autocrine action of IL-6 induced by histamine, since either neutralization of IL-6 by polyclonal antibody or blocking the IL-6 receptor by specific monoclonal antibody abolished the effect of histamine.

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Year:  1993        PMID: 8473012      PMCID: PMC1421817     

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  20 in total

Review 1.  Interleukin 6 in infection and cancer.

Authors:  P B Sehgal
Journal:  Proc Soc Exp Biol Med       Date:  1990-11

Review 2.  Histamine: an early messenger in inflammatory and immune reactions.

Authors:  A Falus; K Merétey
Journal:  Immunol Today       Date:  1992-05

3.  Histamine influences the expression of the interleukin-6 receptor on human lymphoid, monocytoid and hepatoma cell lines.

Authors:  K Merétey; A Falus; T Taga; T Kishimoto
Journal:  Agents Actions       Date:  1991-05

Review 4.  The influence of histamine on immune and inflammatory responses.

Authors:  D J Beer; S M Matloff; R E Rocklin
Journal:  Adv Immunol       Date:  1984       Impact factor: 3.543

Review 5.  The role of histamine in the neuroendocrine regulation of pituitary hormone secretion.

Authors:  U Knigge; J Warberg
Journal:  Acta Endocrinol (Copenh)       Date:  1991-06

Review 6.  The role of histamine in allergic diseases.

Authors:  M V White
Journal:  J Allergy Clin Immunol       Date:  1990-10       Impact factor: 10.793

7.  Modulation of cellular-immune responses in vivo and in vitro by histamine receptor-bearing lymphocytes.

Authors:  R E Rocklin
Journal:  J Clin Invest       Date:  1976-04       Impact factor: 14.808

8.  Effects of histamine on monocyte complement production. I. Inhibition of C2 production mediated by its action on H2 receptors.

Authors:  D Lappin; K Whaley
Journal:  Clin Exp Immunol       Date:  1980-09       Impact factor: 4.330

9.  Histamine modulates the production of interferon-gamma and interleukin-2 by mitogen-activated human mononuclear blood cells.

Authors:  R Carlsson; M Dohlsten; H O Sjögren
Journal:  Cell Immunol       Date:  1985-11       Impact factor: 4.868

10.  Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA.

Authors:  C Auffray; F Rougeon
Journal:  Eur J Biochem       Date:  1980-06
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  6 in total

1.  Histamine content in lymph nodes from patients with malignant lymphomas.

Authors:  A Belcheva; R Mishkova
Journal:  Inflamm Res       Date:  1995-04       Impact factor: 4.575

2.  Histamine selectively enhances human immunoglobulin E (IgE) and IgG4 production induced by anti-CD58 monoclonal antibody.

Authors:  H Kimata; M Fujimoto; C Ishioka; A Yoshida
Journal:  J Exp Med       Date:  1996-08-01       Impact factor: 14.307

3.  Can the therapeutic effects of temozolomide be potentiated by stimulating AMP-activated protein kinase with olanzepine and metformin?

Authors:  R E Kast; G Karpel-Massler; M-E Halatsch
Journal:  Br J Pharmacol       Date:  2011-11       Impact factor: 8.739

Review 4.  OPALS: A New Osimertinib Adjunctive Treatment of Lung Adenocarcinoma or Glioblastoma Using Five Repurposed Drugs.

Authors:  Richard E Kast; Marc-Eric Halatsch; Rafael Rosell
Journal:  Cells       Date:  2021-05-10       Impact factor: 6.600

5.  Critical role of endogenous histamine in promoting end-organ tissue injury in sepsis.

Authors:  Mizuki Hattori; Mitsuaki Yamazaki; Wakana Ohashi; Satoshi Tanaka; Kohshi Hattori; Kenichiro Todoroki; Toshio Fujimori; Hiroshi Ohtsu; Naoyuki Matsuda; Yuichi Hattori
Journal:  Intensive Care Med Exp       Date:  2016-11-08

6.  Blocking epithelial-to-mesenchymal transition in glioblastoma with a sextet of repurposed drugs: the EIS regimen.

Authors:  Richard E Kast; Nicolas Skuli; Georg Karpel-Massler; Guido Frosina; Timothy Ryken; Marc-Eric Halatsch
Journal:  Oncotarget       Date:  2017-06-01
  6 in total

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