Literature DB >> 8472499

The combination of hydroxyurea and leucapheresis in the treatment of chronic myeloid leukaemia in pregnancy.

J M Fitzgerald1, S R McCann.   

Abstract

Treatment of malignancy during pregnancy is difficult because of the potential teratogenicity of chemotherapeutic agents. Leucapheresis was employed in the initial management of a pregnant patient with chronic myeloid leukaemia. It was subsequently replaced with oral hydroxyurea during the second trimester. Successful delivery of a live male infant was achieved and the child has normal growth and development to date.

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Year:  1993        PMID: 8472499     DOI: 10.1111/j.1365-2257.1993.tb00123.x

Source DB:  PubMed          Journal:  Clin Lab Haematol        ISSN: 0141-9854


  2 in total

Review 1.  Pregnancies in patients with chronic myeloid leukemia in the era of imatinib.

Authors:  Liang-Piu Koh; Devendra Kanagalingam
Journal:  Int J Hematol       Date:  2006-12       Impact factor: 2.490

Review 2.  Management of chronic myeloid leukemia in the setting of pregnancy: when is leukocytapheresis appropriate? A case report and review of the literature.

Authors:  Elizabeth M Staley; Sierra C Simmons; Alexander Z Feldman; Robin G Lorenz; Marisa B Marques; Lance A Williams; X Long Zheng; Huy P Pham
Journal:  Transfusion       Date:  2017-12-11       Impact factor: 3.157

  2 in total

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