[Microbial saprotrophic pharmacotherapy: the possible indications, the conditions for its realization and the overall strategy].

Potential indications for bacterial strains-producers of biologically active substances to be utilized for microbial saprotrophic pharmacotherapy are presented. These indications include some infectious diseases and tumors, a number of noninfectious diseases, transplantation and contraception. The cardinal problem of microbial pharmacotherapy, the capacity of strains-producers of getting acclimatized to the patient organism, is discussed. For its solution, a "microbiological passportization of a patient" ("saprotrophic mapping"), that is drawing up a map of patient microbiological status, is proposed. This "saprotrophic secretory passportization (mapping)" of strains-producers is first submitted for consideration. A strategy of future microbial pharmacotherapy is stated. The necessity of careful approbation of this kind of therapy is emphasized.