Literature DB >> 8471368

Minimum alveolar concentration of sevoflurane in elderly patients.

R Nakajima1, Y Nakajima, K Ikeda.   

Abstract

We have determined the minimum alveolar concentration (MAC) for sevoflurane in elderly patients (mean age 71.4 yr). MAC was found to be 1.48 (SEM 0.08)%, which is smaller than the values for children and adults. The magnitude of the change in MAC with age is similar to that for halothane and isoflurane. The calculated anesthetic ED95 for preventing 95% of patients from moving was 1.98%.

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Year:  1993        PMID： 8471368     DOI： 10.1093/bja/70.3.273

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN： 0007-0912            Impact factor:   9.166


  8 in total

Review 1.  [Pharmacokinetic-pharmacodynamic models for inhaled anaesthetics].

Authors:  S Kreuer; J Bruhn; W Wilhelm; T Bouillon
Journal:  Anaesthesist       Date:  2007-06       Impact factor: 1.041

2.  Potentiation by sevoflurane of the gamma-aminobutyric acid-induced chloride current in acutely dissociated CA1 pyramidal neurones from rat hippocampus.

Authors:  J Wu; N Harata; N Akaike
Journal:  Br J Pharmacol       Date:  1996-11       Impact factor: 8.739

Review 3.  Sevoflurance: approaching the ideal inhalational anesthetic. a pharmacologic, pharmacoeconomic, and clinical review.

Authors:  L Delgado-Herrera; R D Ostroff; S A Rogers
Journal:  CNS Drug Rev       Date:  2001

Review 4.  Sevoflurane. A review of its pharmacodynamic and pharmacokinetic properties and its clinical use in general anaesthesia.

Authors:  S S Patel; K L Goa
Journal:  Drugs       Date:  1996-04       Impact factor: 9.546

Review 5.  Anaesthesia and postoperative analgesia in older patients with chronic obstructive pulmonary disease: special considerations.

Authors:  Eva M Gruber; Edda M Tschernko
Journal:  Drugs Aging       Date:  2003       Impact factor: 3.923

6.  The optimal anesthetic depth for interventional neuroradiology: comparisons between light anesthesia and deep anesthesia.

Authors:  Yoo Sun Jung; Ye-Reum Han; Eun-Su Choi; Byung-Gun Kim; Hee-Pyoung Park; Jung-Won Hwang; Young-Tae Jeon
Journal:  Korean J Anesthesiol       Date:  2015-03-30

Review 7.  A clinical review of inhalation anesthesia with sevoflurane: from early research to emerging topics.

Authors:  Jorge D Brioni; Shane Varughese; Raza Ahmed; Berthold Bein
Journal:  J Anesth       Date:  2017-06-05       Impact factor: 2.078

8.  A feasibility study of jaw thrust as an indicator assessing adequate depth of anesthesia for insertion of supraglottic airway device in morbidly obese patients.

Authors:  Lei Wan; Liu-Jia-Zi Shao; Yang Liu; Hai-Xia Wang; Fu-Shan Xue; Ming Tian
Journal:  Chin Med J (Engl)       Date:  2019-09-20       Impact factor: 2.628
  8 in total

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