An analytical approach for reducing workplace health hazards through substitution.

Substitution for a harmful chemical implies that the desired function is maintained without using the harmful chemical in question. Improvement can be achieved if a less harmful chemical can be used or the same function obtained by changing the process and eliminating the harmful chemical agent. In 1982, Denmark introduced an authority regulation requiring substitution if functional and economical alternatives exist. This paper summarizes the results of 162 examples of substitution investigated by the Danish Occupational Health Services. The identification and implementation of substitution alternatives is described as an iterative process with seven distinct steps. Several tools that are useful in evaluating alternatives are described, including Hansen solubility parameters and vapor hazard ratios. In addition to the technical issues surrounding substitution, this paper describes the social interactions necessary to include all affected individuals, along with those having the proper expertise in the decision-making process. The use of the described methods may result in a safer work-place by eliminating certain hazardous chemicals or practices that have historically been used in specific industries.