Literature DB >> 8469282

Instability and decay of the primary structure of DNA.

T Lindahl1.   

Abstract

Although DNA is the carrier of genetic information, it has limited chemical stability. Hydrolysis, oxidation and nonenzymatic methylation of DNA occur at significant rates in vivo, and are counteracted by specific DNA repair processes. The spontaneous decay of DNA is likely to be a major factor in mutagenesis, carcinogenesis and ageing, and also sets limits for the recovery of DNA fragments from fossils.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8469282     DOI： 10.1038/362709a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  1441 in total

1.  A novel role for Escherichia coli endonuclease VIII in prevention of spontaneous G-->T transversions.

Authors:  J O Blaisdell; Z Hatahet; S S Wallace
Journal:  J Bacteriol       Date:  1999-10       Impact factor: 3.490

2.  Abasic sites in duplex DNA: molecular modeling of sequence-dependent effects on conformation.

Authors:  L Ayadi; C Coulombeau; R Lavery
Journal:  Biophys J       Date:  1999-12       Impact factor: 4.033

Review 3.  Survival of life on asteroids, comets and other small bodies.

Authors:  B C Clark; A L Baker; A F Cheng; S J Clemett; D McKay; H Y McSween; C M Pieters; P Thomas; M Zolensky
Journal:  Orig Life Evol Biosph       Date:  1999-10       Impact factor: 1.950

4.  A read-ahead function in archaeal DNA polymerases detects promutagenic template-strand uracil.

Authors:  M A Greagg; M J Fogg; G Panayotou; S J Evans; B A Connolly; L H Pearl
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

5.  Protein preservation and DNA retrieval from ancient tissues.

Authors:  H N Poinar; B A Stankiewicz
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-20       Impact factor: 11.205

6.  Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells.

Authors:  E Sonoda; M S Sasaki; C Morrison; Y Yamaguchi-Iwai; M Takata; S Takeda
Journal:  Mol Cell Biol       Date:  1999-07       Impact factor: 4.272

7.  Inverse radiation dose-rate effects on somatic and germ-line mutations and DNA damage rates.

Authors:  M M Vilenchik; A G Knudson
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-09       Impact factor: 11.205

8.  Characterization of a thermostable DNA glycosylase specific for U/G and T/G mismatches from the hyperthermophilic archaeon Pyrobaculum aerophilum.

Authors:  H Yang; S Fitz-Gibbon; E M Marcotte; J H Tai; E C Hyman; J H Miller
Journal:  J Bacteriol       Date:  2000-03       Impact factor: 3.490

9.  Interactions of the human, rat, Saccharomyces cerevisiae and Escherichia coli 3-methyladenine-DNA glycosylases with DNA containing dIMP residues.

Authors:  M Saparbaev; J C Mani; J Laval
Journal:  Nucleic Acids Res       Date:  2000-03-15       Impact factor: 16.971

10.  A method for detecting abasic sites in living cells: age-dependent changes in base excision repair.

Authors:  H Atamna; I Cheung; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-18       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.