| Literature DB >> 8468102 |
H Yamashita1, M Yamamoto, Y Sato, T Izawa, T Komabayashi, D Saito, H Ohno.
Abstract
The effect was investigated of endurance training on the expression of uncoupling protein (UCP) mRNA in brown adipose tissue (BAT) of rats. The exercised rats were trained on a rodent treadmill for 5 days per week and a total of 9 weeks. After the training programme, a marked decrease in BAT mass was found in terms of weight or weight per unit body weight; there was a corresponding decrease in DNA content and a downward trend in RNA and glycogen levels. The UCP mRNA was present at a markedly decreased level in BAT of trained animals. In consideration of the reduced levels of mRNAs for hormone-sensitive lipase and acyl-CoA synthetase, the brown adipose tissue investigated appeared to be in a relatively atrophied and thermogenically quiescent state.Entities:
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Year: 1993 PMID： 8468102 DOI： 10.1007/bf01212769
Source DB: PubMed Journal: Int J Biometeorol ISSN： 0020-7128 Impact factor: 3.787