| Literature DB >> 8468047 |
J M Hoovers1, E Redeker, F Speleman, J W Höppener, S Bhola, J Bliek, N van Roy, N J Leschot, A Westerveld, M Mannens.
Abstract
We report the high-resolution localization of the human calcitonin/CGRP genes, CALCA, CALCB, and the pseudogene CALCP, to a 220-kb SacII fragment on chromosome 11p15.2-p15.1, using prometaphase fluorescence in situ hybridization (FISH), two-color interphase FISH, and pulsed-field gel electrophoresis analysis. The related islet amyloid polypeptide (IAPP) gene was assigned to human chromosome 12p12.3-p12.1. The results support an evolutionary relationship between the calcitonin/CGRP genes and the IAPP gene and between parts of human chromosomes 11 and 12.Entities:
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Year: 1993 PMID： 8468047 DOI： 10.1006/geno.1993.1104
Source DB: PubMed Journal: Genomics ISSN： 0888-7543 Impact factor: 5.736