Literature DB >> 8466955

Determination of thiol-containing drugs by chemiluminescence-flow injection analysis.

P Viñas1, I Lopez Garcia, J A Martinez Gil.   

Abstract

A flow injection analysis procedure with chemiluminescence detection for the determination of both thiol-containing drugs and the amino acid cysteine is described. Procedures are based on the inhibition by the drugs of the chemiluminescence generated in the copper-catalysed oxidation of luminol by hydrogen peroxide. The proposed methods were applied to the determination of cysteine, N-acetylcysteine, penicillamine, 2-mercaptopropionylglycine and thiouracil in pharmaceuticals.

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Year:  1993        PMID: 8466955     DOI: 10.1016/0731-7085(93)80144-p

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN: 0731-7085            Impact factor:   3.935


  1 in total

1.  Flow injection spectrophotometric determination of N-acetyl-L-cysteine as a complex with palladium(II).

Authors:  Josipa Giljanović; Mia Brkljača; Ante Prkić
Journal:  Molecules       Date:  2011-08-25       Impact factor: 4.411

  1 in total

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