Literature DB >> 8466529

Molecular cloning and sequencing of zeta-crystallin/quinone reductase cDNA from human liver.

P Gonzalez1, P V Rao, J S Zigler.   

Abstract

Zeta-crystallin is an enzyme-crystallin highly expressed in the lens of some hystricomorph rodents and camels. It has been shown to have a novel NADPH: quinone oxidoreductase activity and is present at enzymatic levels in a variety of tissues from various mammals. We report here the cDNA cloning of zeta-crystallin from a human liver library. One clone with the complete open reading frame was obtained. Ten nucleotides of the 5' and 796 of the 3' nontranslated regions are present in the clone including two possible polyadenylation signals. The deduced amino acid sequence is 328 residues long with a calculated molecular mass of 34910 daltons and isoelectric point of 8.73. It shows 84% identity with the guinea pig protein.

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Year:  1993        PMID： 8466529     DOI： 10.1006/bbrc.1993.1302

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  7 in total

1.  Crystal structures of the quinone oxidoreductase from Thermus thermophilus HB8 and its complex with NADPH: implication for NADPH and substrate recognition.

Authors:  Yoshimitsu Shimomura; Yoshimitsu Kakuta; Keiichi Fukuyama
Journal:  J Bacteriol       Date:  2003-07       Impact factor: 3.490

2.  Inhibition of zeta-crystallin by Coumarins: a structure-activity study.

Authors:  A S Duhaiman
Journal:  J Protein Chem       Date:  1996-04

3.  Structure and alternate tissue-preferred transcription initiation of the mouse alpha B-crystallin/small heat shock protein gene.

Authors:  P H Frederikse; R A Dubin; J I Haynes; J Piatigorsky
Journal:  Nucleic Acids Res       Date:  1994-12-25       Impact factor: 16.971

4.  Expression and purification of his-tagged recombinant mouse zeta-crystallin.

Authors:  Mukoma F Simpanya; Victor R Leverenz; Frank J Giblin
Journal:  Protein Expr Purif       Date:  2009-08-11       Impact factor: 1.650

5.  zeta-Crystallin is a bcl-2 mRNA binding protein involved in bcl-2 overexpression in T-cell acute lymphocytic leukemia.

Authors:  Andrea Lapucci; Matteo Lulli; Amedeo Amedei; Laura Papucci; Ewa Witort; Federico Di Gesualdo; Francesco Bertolini; Gary Brewer; Angelo Nicolin; Annamaria Bevilacqua; Nicola Schiavone; Dominique Morello; Martino Donnini; Sergio Capaccioli
Journal:  FASEB J       Date:  2010-01-26       Impact factor: 5.191

6.  Isolation of a single-stranded DNA-binding protein from the methylotrophic yeast, Pichia pastoris and its identification as zeta crystallin.

Authors:  Balla Venkata Kranthi; Natarajan Balasubramanian; Pundi N Rangarajan
Journal:  Nucleic Acids Res       Date:  2006-08-16       Impact factor: 16.971

7.  Structural Insights into the NAD(P)H:Quinone Oxidoreductase from Phytophthora capsici.

Authors:  Cancan Yang; Zhenling Huang; Xiuguo Zhang; Chunyuan Zhu
Journal:  ACS Omega       Date:  2022-07-13
  7 in total

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