| Literature DB >> 8466471 |
Abstract
Normal meiosis consists of a single round of DNA replication followed by two nuclear divisions. In the 1st division the chromosomes segregate reductionally whereas in the 2nd division they segregate equationally (as they do in mitosis). In certain yeast mutants, a single-division meiosis takes place, in which some chromosomes segregate reductionally while others divide equationally. This autonomous segregation behaviour of individual chromosomes on a common spindle is determined by the centromeres they carry. The relationship between reductional segregation of a pair of chromosomes and their earlier recombinational history is also discussed.Entities:
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Year: 1993 PMID: 8466471 DOI: 10.1002/bies.950150102
Source DB: PubMed Journal: Bioessays ISSN: 0265-9247 Impact factor: 4.345