| Literature DB >> 8465888 |
M D De Bellis1, P W Gold, T D Geracioti, S J Listwak, M A Kling.
Abstract
The authors measured CSF concentrations of corticotropin-releasing hormone (CRH) and arginine vasopressin in nine depressed patients before and after fluoxetine treatment. They found significant decreases in CSF CRH, CSF arginine vasopressin, and Hamilton depression ratings. Thus, the therapeutic effect of this serotonin-uptake inhibitor may be related to diminution of these arousal-promoting neuropeptides.Entities:
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Year: 1993 PMID: 8465888 DOI: 10.1176/ajp.150.4.656
Source DB: PubMed Journal: Am J Psychiatry ISSN: 0002-953X Impact factor: 18.112