OBJECTIVE: The authors examined the course of depression over 2 years for outpatients with and without a history of hypertension, a history of myocardial infarction, or current insulin-dependent diabetes. METHOD: Among outpatient visitors to the practices of 523 general medical clinicians and mental health specialists, 626 depressed patients were followed for 1 or 2 years with a telephone-administered interview based on the format of the National Institute of Mental Health Diagnostic Interview Schedule. RESULTS: Depressed patients with and without medical illness had high rates of persistent depressive symptoms and spells over 2 years. Patients with a lifetime history of myocardial infarction had significantly more spells of depression over the first follow-up year, more total symptoms of depression in the second follow-up year, and more depressive symptoms at the end of each follow-up year than depressed patients without myocardial infarction. The course of depression did not differ significantly for depressed patients with and without a lifetime history of hypertension or current insulin-dependent diabetes. CONCLUSIONS: Among depressed adult outpatients, a history of myocardial infarction is associated with a particularly poor clinical prognosis. A relatively high percentage of all depressed patients in this study had persistent depression regardless of the extent of medical comorbidity.
OBJECTIVE: The authors examined the course of depression over 2 years for outpatients with and without a history of hypertension, a history of myocardial infarction, or current insulin-dependent diabetes. METHOD: Among outpatient visitors to the practices of 523 general medical clinicians and mental health specialists, 626 depressedpatients were followed for 1 or 2 years with a telephone-administered interview based on the format of the National Institute of Mental Health Diagnostic Interview Schedule. RESULTS:Depressedpatients with and without medical illness had high rates of persistent depressive symptoms and spells over 2 years. Patients with a lifetime history of myocardial infarction had significantly more spells of depression over the first follow-up year, more total symptoms of depression in the second follow-up year, and more depressive symptoms at the end of each follow-up year than depressedpatients without myocardial infarction. The course of depression did not differ significantly for depressedpatients with and without a lifetime history of hypertension or current insulin-dependent diabetes. CONCLUSIONS: Among depressed adult outpatients, a history of myocardial infarction is associated with a particularly poor clinical prognosis. A relatively high percentage of all depressedpatients in this study had persistent depression regardless of the extent of medical comorbidity.
Authors: Marcus Ising; Susanne Lucae; Elisabeth B Binder; Thomas Bettecken; Manfred Uhr; Stephan Ripke; Martin A Kohli; Johannes M Hennings; Sonja Horstmann; Stefan Kloiber; Andreas Menke; Brigitta Bondy; Rainer Rupprecht; Katharina Domschke; Bernhard T Baune; Volker Arolt; A John Rush; Florian Holsboer; Bertram Müller-Myhsok Journal: Arch Gen Psychiatry Date: 2009-09
Authors: In Kyoon Lyoo; Sujung Yoon; Alan M Jacobson; Jaeuk Hwang; Gail Musen; Jieun E Kim; Donald C Simonson; Sujin Bae; Nicolas Bolo; Dajung J Kim; Katie Weinger; Junghyun H Lee; Christopher M Ryan; Perry F Renshaw Journal: Arch Gen Psychiatry Date: 2012-12
Authors: Tanya A. Zielinski; E Sherwood Brown; Vicki A. Nejtek; David A. Khan; Jacob J. Moore; A John Rush Journal: Prim Care Companion J Clin Psychiatry Date: 2000-10
Authors: Jacob N de Voogd; Johan B Wempe; Klaas Postema; Eric van Sonderen; Adelita V Ranchor; James C Coyne; Robbert Sanderman Journal: Ann Behav Med Date: 2009-10