OBJECTIVE: To investigate the ability of immediate postpartum curettage to accelerate maternal recovery from severe preeclampsia. METHODS:Thirty-two parturients with severe preeclampsia were randomly assigned to either undergo ultrasound-directed curettage following delivery or to have no curettage. RESULTS: Subjects who underwent immediate postpartum curettage had a significantly decreased mean arterial pressure at each 2-hour point for the first 24 hours compared with those who were not curetted (P < .0002). The mean urine output after uterine curettage was significantly greater during each 4-hour interval of the first 24 hours postpartum compared with controls (P < .0002). The platelet count increased in the curettage group from 12 to 24 hours following curettage, whereas controls exhibited a decrease in the platelet count from 12 to 24 hours (P < .0003). CONCLUSION: Immediate puerperal uterine curettage of the parturient with severe preeclampsia appears to accelerate disease recovery with no apparent adverse sequelae.
RCT Entities:
OBJECTIVE: To investigate the ability of immediate postpartum curettage to accelerate maternal recovery from severe preeclampsia. METHODS: Thirty-two parturients with severe preeclampsia were randomly assigned to either undergo ultrasound-directed curettage following delivery or to have no curettage. RESULTS: Subjects who underwent immediate postpartum curettage had a significantly decreased mean arterial pressure at each 2-hour point for the first 24 hours compared with those who were not curetted (P < .0002). The mean urine output after uterine curettage was significantly greater during each 4-hour interval of the first 24 hours postpartum compared with controls (P < .0002). The platelet count increased in the curettage group from 12 to 24 hours following curettage, whereas controls exhibited a decrease in the platelet count from 12 to 24 hours (P < .0003). CONCLUSION: Immediate puerperal uterine curettage of the parturient with severe preeclampsia appears to accelerate disease recovery with no apparent adverse sequelae.
Authors: Tamara Garrido-Gomez; Francisco Dominguez; Alicia Quiñonero; Patricia Diaz-Gimeno; Mirhan Kapidzic; Matthew Gormley; Katherine Ona; Pablo Padilla-Iserte; Michael McMaster; Olga Genbacev; Alfredo Perales; Susan J Fisher; Carlos Simón Journal: Proc Natl Acad Sci U S A Date: 2017-09-18 Impact factor: 11.205
Authors: Alexandra E Cairns; Louise Pealing; James M N Duffy; Nia Roberts; Katherine L Tucker; Paul Leeson; Lucy H MacKillop; Richard J McManus Journal: BMJ Open Date: 2017-11-28 Impact factor: 2.692