Literature DB >> 8459652

Expression and functional characterization of a rat sulfotransferase (ST1A1) cDNA for sulfations of phenolic substrates in COS-1 cells.

S Ozawa1, K Nagata, D W Gong, Y Yamazoe, R Kato.   

Abstract

A cDNA (PST-1) isolated from a rat liver cDNA library was expressed in COS-1 cells and found to encode a form of arylsulfotransferase (termed ST1A1), which sulfated p-nitrophenol, alpha-naphthol, minoxidil, beta-estradiol and dopamine, but not dehydroepiandrosterone and cortisol. ST1A1 showed a mobility identical with a major immunodetectable sulfotransferase contained in the livers of male and female rats in Western blots. In addition, ST1A1 mRNA was detected in the liver and extrahepatic tissues by Northern blots.

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Year:  1993        PMID： 8459652     DOI： 10.1254/jjp.61.153

Source DB:  PubMed          Journal:  Jpn J Pharmacol        ISSN： 0021-5198


  4 in total

1.  Mechanisms of gender-specific regulation of mouse sulfotransferases (Sults).

Authors:  Yazen Alnouti; Curtis D Klaassen
Journal:  Xenobiotica       Date:  2010-11-23       Impact factor: 1.908

2.  Characterization of bovine tracheobronchial phenol sulphotransferase cDNA and detection of mRNA regulation by cortisol.

Authors:  S J Schauss; T Henry; R Palmatier; L Halvorson; R Dannenbring; J D Beckmann
Journal:  Biochem J       Date:  1995-10-01       Impact factor: 3.857

3.  Activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b] pyridine by cDNA-expressed human and rat arylsulfotransferases.

Authors:  S Ozawa; H C Chou; F F Kadlubar; K Nagata; Y Yamazoe; R Kato
Journal:  Jpn J Cancer Res       Date:  1994-12

4.  Formation of 2-amino-3-methylimidazo[4,5-f]quinoline- and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-sulfamates by cDNA-expressed mammalian phenol sulfotransferases.

Authors:  S Ozawa; K Nagata; Y Yamazoe; R Kato
Journal:  Jpn J Cancer Res       Date:  1995-03
  4 in total

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