Literature DB >> 8458415

Purification of macrophage migration inhibitory factor (MIF) from bovine brain cytosol.

A Galat1, S Rivière, F Bouet.   

Abstract

Two isoforms of the macrophage migration inhibitory factor (MIF) have been isolated to homogeneity from bovine brain cytosol. In agreement with the cDNA sequence of their human counterpart, they both have an apparent molecular weight of 12 kDa and are characterized by the following N-terminal amino acid sequence NH2-PMFVVNTNVPRASVPDGLLSELTQQLAQATGKPPQYIAV-. CD spectra revealed that bovine MIF contains 42% (+/- 3%) alpha-helix and 21% (+/- 3%) beta-structure. CD-constrained prediction of the secondary structure assigned MIF to the alpha/beta-class of proteins.

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Year:  1993        PMID： 8458415     DOI： 10.1016/0014-5793(93)80553-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  9 in total

1.  Migration inhibitory factor expression in experimentally induced endotoxemia.

Authors:  M Bacher; A Meinhardt; H Y Lan; W Mu; C N Metz; J A Chesney; T Calandra; D Gemsa; T Donnelly; R C Atkins; R Bucala
Journal:  Am J Pathol       Date:  1997-01       Impact factor: 4.307

2.  MIF expression in the rat brain: implications for neuronal function.

Authors:  M Bacher; A Meinhardt; H Y Lan; F S Dhabhar; W Mu; C N Metz; J A Chesney; D Gemsa; T Donnelly; R C Atkins; R Bucala
Journal:  Mol Med       Date:  1998-04       Impact factor: 6.354

3.  Deficiency of the macrophage migration inhibitory factor gene has no significant effect on endotoxaemia.

Authors:  N Honma; H Koseki; T Akasaka; T Nakayama; M Taniguchi; I Serizawa; H Akahori; M Osawa; T Mikayama
Journal:  Immunology       Date:  2000-05       Impact factor: 7.397

4.  The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction.

Authors:  E Rosengren; R Bucala; P Aman; L Jacobsson; G Odh; C N Metz; H Rorsman
Journal:  Mol Med       Date:  1996-01       Impact factor: 6.354

5.  NMR characterization of structure, backbone dynamics, and glutathione binding of the human macrophage migration inhibitory factor (MIF).

Authors:  P Mühlhahn; J Bernhagen; M Czisch; J Georgescu; C Renner; A Ross; R Bucala; T A Holak
Journal:  Protein Sci       Date:  1996-10       Impact factor: 6.725

6.  Identification of macrophage migration inhibitory factor isoforms in bovine brain.

Authors:  B Y Gurvits; O Y Tretyakov; N V Klishina; S Stoeva; W Voelter; A A Galoyan
Journal:  Neurochem Res       Date:  2000-08       Impact factor: 3.996

7.  Charge heterogeneity of bovine brain macrophage migration inhibitory factor.

Authors:  O A Cherepkova; E M Lutova; B Ya Gurvits
Journal:  Neurochem Res       Date:  2005-01       Impact factor: 3.996

8.  Macrophage migration inhibitory factor: identification of the 30-kDa MIF-related protein in bovine brain.

Authors:  O A Cherepkova; B Ya Gurvits
Journal:  Neurochem Res       Date:  2004-07       Impact factor: 3.996

9.  Direct link between cytokine activity and a catalytic site for macrophage migration inhibitory factor.

Authors:  M Swope; H W Sun; P R Blake; E Lolis
Journal:  EMBO J       Date:  1998-07-01       Impact factor: 11.598
  9 in total

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