Literature DB >> 8457148

Alkaloids of Cynanchum vincetoxicum: efficacy against MDA-MB-231 mammary carcinoma cells.

U Tanner1, W Wiegrebe.   

Abstract

Alkaloids 1-4 from Cynanchum vincetoxicum (asclepiadaceae) (Scheme 1) do not have affinity to the oestrogen receptor but they inhibit the growth of the hormone-independent mammary carcinoma cells MDA-MB-231 (Fig. 1) and bind to nucleosides and nucleotides (Table 1). Intercalation was not observed.

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Year:  1993        PMID: 8457148     DOI: 10.1002/ardp.19933260203

Source DB:  PubMed          Journal:  Arch Pharm (Weinheim)        ISSN: 0365-6233            Impact factor:   3.751


  2 in total

1.  Synthesis, biological evaluation and mechanism studies of deoxytylophorinine and its derivatives as potential anticancer agents.

Authors:  Haining Lv; Jinhong Ren; Shuanggang Ma; Song Xu; Jing Qu; Zhenjia Liu; Qing Zhou; Xiaoguang Chen; Shishan Yu
Journal:  PLoS One       Date:  2012-01-19       Impact factor: 3.240

Review 2.  Ethnobotany, Phytochemistry and Pharmacological Effects of Plants in Genus Cynanchum Linn. (Asclepiadaceae).

Authors:  Lu Han; Xiuping Zhou; Mengmeng Yang; Li Zhou; Xinxin Deng; Shijie Wei; Wenping Wang; Zhizhong Wang; Xue Qiao; Changcai Bai
Journal:  Molecules       Date:  2018-05-16       Impact factor: 4.411

  2 in total

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