| Literature DB >> 8456560 |
J Knüver-Hopf1, H Heinze, B Lambrecht, H Mohr, J Beyer, H Schmitt.
Abstract
The presence of IgM antibodies to human immunodeficiency virus 1 (HIV-1) was investigated in blood donor sera which were indeterminate in anti-HIV-1 IgG Western blot testing. In 7 of 173 instances out of approximately 1,000,000 blood donation sera with an isolated anti-p24 IgG produced an anti-gp41-45 IgM immunoblot reaction. Applying polymerase chain reaction (PCR) to 29 indeterminate samples out of approximately 125,000 blood donations it was found that 2 of them were IgM-positive and also contained HIV-1-specific DNA sequences. Eleven months later 1 of these 2 donors was retested and found IgM and PCR negative.Entities:
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Year: 1993 PMID： 8456560 DOI： 10.1111/j.1423-0410.1993.tb02524.x
Source DB: PubMed Journal: Vox Sang ISSN： 0042-9007 Impact factor: 2.144