Literature DB >> 8455434

The use of magnetic resonance imaging to track controlled drug release and transport in the brain.

B Reisfeld1, S Blackband, V Calhoun, S Grossman, S Eller, K Leong.   

Abstract

A method has been developed to track controlled drug release and transport in the brain. This method entails the use of a polymeric implant to release, over time, a paramagnetically labelled compound into the brain. Magnetic resonance imaging is used to determine the evolving concentration distribution. This method is well suited to other types of intracranial drug delivery systems as well as to track transport in other organs of the body.

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Year:  1993        PMID： 8455434     DOI： 10.1016/0730-725x(93)90029-d

Source DB:  PubMed          Journal:  Magn Reson Imaging        ISSN： 0730-725X            Impact factor:   2.546


  4 in total

1.  Drug elimination kinetics following subconjunctival injection using dynamic contrast-enhanced magnetic resonance imaging.

Authors:  Stephanie H Kim; Karl G Csaky; Nam Sun Wang; Robert J Lutz
Journal:  Pharm Res       Date:  2007-08-03       Impact factor: 4.200

Review 2.  Localized delivery of proteins in the brain: can transport be customized?

Authors:  M F Haller; W M Saltzman
Journal:  Pharm Res       Date:  1998-03       Impact factor: 4.200

3.  In vitro/in vivo comparison of drug release and polymer erosion from biodegradable P(FAD-SA) polyanhydrides--a noninvasive approach by the combined use of electron paramagnetic resonance spectroscopy and nuclear magnetic resonance imaging.

Authors:  K Mäder; Y Crémmilleux; A J Domb; J F Dunn; H M Swartz
Journal:  Pharm Res       Date:  1997-06       Impact factor: 4.200

Review 4.  Biomedical Imaging in Implantable Drug Delivery Systems.

Authors:  Haoyan Zhou; Christopher Hernandez; Monika Goss; Anna Gawlik; Agata A Exner
Journal:  Curr Drug Targets       Date:  2015       Impact factor: 3.465
  4 in total

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